AAN 2023: Brigham Neurologists Present Latest Research

3d rendering of a brain

On April 22–27, 2023, the American Academy of Neurology hosts its 75th annual meeting in Boston, MA and virtually. Leaders from the Department of Neurology at Brigham and Women’s Hospital will present their latest research at the meeting alongside international colleagues.


Sonographic B-lines Facilitate Detection of Pulmonary Congestion After Acute MI

Doctor performs chest ultrasound on man in hospital closeup

Researchers at Brigham and Women’s Hospital are the first to study the long-term trajectory of lung ultrasound findings after acute myocardial infarction (AMI). They conclude that quantification of B-lines could facilitate early detection, quantification, and monitoring of pulmonary congestion in AMI patients.


Outcomes Comparable, Operative Time Reduced With Prone-Lateral Single-Position Lumbar Fusion Vs. Staged Procedures

X-ray image of lumbar spine postoperative treatment for degenerative lumbar disc diseaseby decompression and fix by iron rod and screws

Andrew J. Schoenfeld, MD, MSc, at Brigham and Women’s Hospital, Peter G. Passias, MD, and colleagues are the first to examine longer-term outcomes of the prone-lateral variation of circumferential lumbar fusion.


Brigham Neurosurgery at the AANS 2023 Annual Scientific Meeting

Neurosurgeon in special surgery glasses performing operation

Experts from the Department of Neurosurgery at Brigham and Women’s Hospital join other neurosurgical leaders at this year’s AANS Annual Scientific Meeting, “Neurosurgeons as Advocates,” held April 21 – 24, 2023, in Los Angeles, CA.


Clinical and Allergy Profiles of Eosinophilic Esophagitis Differ From GERD

Walter Chan, MD, PhD, of Brigham and Women’s Hospital, and colleagues have reported supporting evidence that proton pump inhibitor (PPI)–responsive eosinophilic esophagitis (EoE) is clinically similar to PPI-nonresponsive EoE and significantly different from erosive esophagitis.


Anterior Temporal Lobectomy Has Clear Utility in Medically Refractory Herpes Simplex Virus Encephalitis

Herpes simplex virus (HSV) is the most common cause of viral encephalitis. The brain lesions in HSV encephalitis (HSVE) primarily involve the temporal and frontal lobes. About half of patients develop seizures, which may progress to chronic seizure disorders or status epilepticus.


Grinding, Clicking and Pivot Pain Usually Resolve After Knee Arthroscopy

Runner stopped on road holding knee in pain, knee symptoms

Elizabeth G. Matzkin, MD, of the Women’s Sports Medicine Program, and colleagues study the benefit of arthroscopy for individual knee symptoms. They report two-thirds of patients experienced resolution of grinding/clicking and pivot pain, but fewer had resolution of catching/locking.


Durable Diabetes Remission More Likely After Bariatric Surgery Than Medical/Lifestyle Therapy

Team of surgeons in operating room

Few surgeons perform metabolic surgery for type 2 diabetes treatment, citing inadequate evidence, and for the same reason, many health insurance plans don’t cover it. Long-term supportive efficacy data from the largest randomized cohort has been published.


Palmitoylation of Syt11 Explains Parkinson’s Disease Risk, May Be Targetable

Gary P.H. Ho, MD, PhD, neurologist in the Ann Romney Center for Neurologic Diseases at Brigham and Women’s Hospital, Dennis J. Selkoe, MD, co-director of the Center, and colleagues suspected there might be a functional link between Syt11 and αS in the context of Parkinson’s disease.