Taking Tumor Boards to the Next Level

Tumor board meeting

While traditional tumor boards are common at most academic medical centers, Dana-Farber/Brigham and Women’s Cancer Center (DF/BWCC) has taken its 10-year-old tumor board to the next level by integrating molecular pathology into their discussions.

Read More

Patient-Reported Outcome Measures Guiding Urology Care

Man on virtual visit on tabletThe Division of Urology at Brigham and Women’s Hospital provides expert, individualized care for a range of urological conditions. Because many urological treatments have similar clinical outcomes, division surgeons are gathering data called patient-reported outcome measures (PROMs). They plan to use PROMs to better identify the nuances of treatment outcomes and determine how these outcomes affect quality of life for individual patients.

Read More

Optimizing Care for Every Patient With Genitourinary Cancer

Masked doctor and patient

Based on clinical expertise and patient volume, the Dana-Farber/Brigham and Women’s Cancer Center (DF/BWCC) is one of the top programs in the country for the treatment of genitourinary cancers. The integrated center draws on the expertise of a multidisciplinary team of specialists to provide exceptional patient care.

Read More

Exploring a New Combination Therapy to Prevent Renal Cell Cancer Recurrence

close-up of cells

Immune checkpoint inhibitors have transformed the management of patients with advanced kidney cancer. However, these therapies only work for a subset of patients with advanced disease and can be associated with substantial side effects. As a result, researchers are focused on new therapeutic combinations to boost the effectiveness of current immune therapies in renal cancer, including in patient populations with early-stage disease that is likely to recur.

Read More

Using Motion-Capture Technology to Advance Ergonomic Studies of Ureteroscopy

Person testing out motion capture technology
Eugene Cone, MD, a Harvard Urologic Oncology Fellow, performs a ureteroscopic simulation task in the motion capture laboratory.

Ureteroscopy is one of the most common procedures performed by urologists. Yet little is known about what optimizes the procedure’s success, especially in terms of how the urologist holds the ureteroscope and which hand and arm movements are most effective.

Read More

Improving Communication and Safety During Urologic Surgery Through Simulation Training

doctor and resident in the operating room

Communication breakdowns and poor teamwork are major contributors to preventable patient harm during surgery. To combat these and other threats to patient safety, surgical teams at Brigham and Women’s Hospital have long been provided with training that simulates crises in the operating room (OR). The proactive nature of these simulations is something that the Brigham’s Division of Urology finds invaluable.

Read More

Research Efforts Focus on Underactive Bladder, a Common but Poorly Understood Condition

Doctor is making notes while listening to his patient

Physicians have a good sense of the symptoms and causes of overactive bladder, and clear guidelines exist for diagnosis. Thanks to advertising for pharmaceuticals and other products, even many members of the general public are aware of this condition and know that treatments are available.

Read More

Researchers Identify Promising New Drug Target for Metastatic Prostate Cancer

Model depicting the mechanism by which selective targeting of PARP-2 attenuates FOXA1/AR signaling and inhibits prostate cancer growth
Model depicting the mechanism by which selective targeting of PARP-2 attenuates FOXA1/AR signaling and inhibits prostate cancer growth.

Although surgery and radiation provide good disease control for localized prostate cancer, developing long-lasting approaches for treating metastatic disease has been challenging because resistance to androgen deprivation therapy (ADT) frequently develops.

Read More

How 2019 Nobel-Winner Kaelin’s Work Changed the Treatment of Kidney Cancer

Members of the Brigham and Women’s Hospital community celebrated in October upon learning that William G. Kaelin Jr., MD, a senior physician-scientist at the Brigham, had won the 2019 Nobel Prize in Physiology or Medicine.

Read More