Optimizing Emergent and Long-Term Care for Aortic Dissection

Dr. Sabe on Aortic Dissections

Timely diagnosis of an acute aortic dissection is the first key step to saving a patient’s life. However, not all hospitals are equipped to handle the next critical step: administering timely treatment to reestablish true lumen flow in the aorta. In these cases, according to an invited expert review published in The Annals of Thoracic Surgery, rapid transfer of the patient to a center of excellence is advisable.

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Preventing Cancer-Associated Thrombosis

Blood clot in the superior vena cava
Blood clot in the superior vena cava associated with a central venous catheter in a 32-year-old woman with Lynch syndrome and advanced colon cancer.

Today’s cancer therapies are helping patients live longer. However, treatments including surgery, radiation, chemotherapy and certain targeted and immunological therapies increase the risk of developing cancer-associated thrombosis (CAT). Physicians at Brigham and Women’s Hospital’s Heart & Vascular Center are working with colleagues at Dana-Farber Cancer Institute (DFCI) to help prevent CAT and minimize its effect on timely cancer care.

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Brigham Offers Comprehensive Approach to Afib Management

Ablation imaging
Detailed, accurate renderings such as this one help guide operators during ablation, without use of fluoroscopy, enabling a safe, effective, and efficient ablation procedure.

The Heart & Vascular Center at Brigham and Women’s Hospital has a well-established reputation for innovation in atrial fibrillation (Afib) treatment. Twenty years ago, the Brigham pioneered cryoablation therapy, which currently comprises about 20 percent of Afib ablations conducted worldwide.

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A Case Study: TAVR in Patient With Congenital Heart Defect

TAVR procedure

Over the past decade, transcatheter aortic valve replacement (TAVR) has evolved from a high-risk procedure to one that has become a standard of care. Each year, thousands of patients undergo this minimally invasive procedure.

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Exploring Potential Cardiac Toxicity of Hydroxychloroquine

bottle of spilled pills

Hydroxychloroquine (HCQ) is a mainstay of therapy for rheumatic diseases such as systemic lupus erythematosus (SLE) and rheumatoid arthritis (RA). However, its use in treating COVID-19 patients in recent months has raised concerns over a possible link to acute cardiac toxicity.

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Major Adverse Cardiovascular Events Associated With COVID-19

patient in hospital bed

Several cardiovascular complications have been associated with COVID-19, according to a recent multicenter, observational cohort study conducted by researchers at Brigham and Women’s Hospital and published in the Journal of the American College of Cardiology.

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Thoracic and Cardiac Surgeons Perform Innovative Resection

Cross-sectional view of yolk sac tumor (YST) surrounding the aorta.
Cross-sectional view of yolk sac tumor (YST) surrounding the aorta.

In the summer of 2019, Paul Pezzote, 67, learned he had Stage 4 cancer. Pezzote, who has Parkinson’s disease, had undergone treatments in 2010 at Dana-Farber/Brigham and Women’s Cancer Center (DF/BWCC). However, the cancer had returned and spread.

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The Brigham Expands Use of ECMO During COVID-19

extracorporeal membrane oxygenation (ECMO) machine

In March of 2020, Brigham and Women’s Hospital purchased four additional extracorporeal membrane oxygenation (ECMO) machines to prepare for a possible surge of COVID-19. It wasn’t yet clear if ECMO could support critically ill COVID-19 patients, but early reports from China had shown promise.

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The Cardiac Amyloidosis Program at Brigham and Women’s

The Cardiac Amyloidosis Program at Brigham and Women’s Hospital was the first of its kind in the United States. Established 10 years ago by Rodney H. Falk, MD, a widely recognized expert in cardiac amyloidosis, the collaborative program has expanded to diagnose and treat every form of amyloidosis, involving experts from cardiology, cardiac pathology, gastroenterology, hematology, nephrology, oncology and neurology.
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Innovations in Transcatheter Mitral Valve Therapies

surgeons in operating room

In the last decade, there has been rapid progress in the treatment of aortic valve disease with catheter-based therapies. For adults with aortic stenosis, transcatheter aortic valve replacement (TAVR) has become commonplace, with Brigham and Women’s Hospital offering the highest-volume TAVR program in New England.

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