Extracorporeal Cardiopulmonary Resuscitation Protocol on Preventing Sudden Cardiac Arrest Deaths

Conventional CPR, which combines rescue breathing with chest compressions, has been the primary treatment for cardiac arrest for nearly 60 years. Survival, however, remains frustratingly low. Brigham and Women’s Hospital is part of a collaborative effort to explore a promising new alternative: extracorporeal…

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Review: When Direct Oral Anticoagulants Should Not Be Standard Treatment

Direct oral anticoagulants (DOACs) are preferred to vitamin K antagonists for stroke prevention in atrial fibrillation, acute treatment and extended-duration secondary prevention of venous thromboembolism in most patients. However, DOACs may be less efficacious or safe compared to standard of care in other conditions.

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Replacement of cTnI With hs-cTnI for Evaluation of Pulmonary Embolism May Misclassify Risk

Behnood Bikdeli, MD, MS, at Brigham and Women’s Hospital, David Jiménez, MD, PhD, at Hospital Ramón y Cajal in Madrid, and colleagues recently conducted the first study to compare the prognostic relevance of cTnI with hs-cTnI in patients with pulmonary embolism (PE).

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Million Veteran Program Affirms Advice to Limit Red Meat Intake

Using a very large U.S. prospective cohort from the Million Veteran Program, Brigham and Women’s Hospital researchers report that a higher intake of red meat, either processed or unprocessed, was associated with a higher risk of cardiovascular disease.

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Heart Rhythm 2024: Brigham Presents Electrophysiology Research

On May 16 – 19, 2024, faculty from the Heart & Vascular Center at Brigham and Women’s Hospital will join the international electrophysiology community and present their latest research at the Heart Rhythm 2024 annual meeting.

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New Research Uncovers Biological Drivers of Heart Disease Risk

Researchers from the Brigham, the Broad Institute, and Stanford Medicine combined multiple sequencing and experimental techniques to map the relationship between known coronary artery disease (CAD) variants and the biological pathways they impact.

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Three Studies Find Statins Protect Against Cardiovascular Disease in High-Risk Groups

Brigham researchers are challenging the trend of deprescribing statins in people over 75 years of age. Ariela Orkaby, MD, MPH, led a trio of studies of statin use in older adults with chronic kidney disease, older adults with and without frailty, and adults with heart failure with preserved ejection fraction.

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New Method of Identifying Disease-associated Traits Could Lead to Better Targeted Therapeutics

Brigham researchers have developed a method for identifying hidden genetic contributors to disease by applying various stress tests to human blood cells. The evoked cellular response traits they observed pinpointed genes and pathways relevant to multiple cardiometabolic and inflammatory diseases.

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Combination of SGLT2i, GLP-1 RA, and Non-Steroidal MRA Proposed for Patients With Type 2 Diabetes and Albuminuria

After analyzing data from pivotal trials, researchers at Brigham and Women’s Hospital believe treatment with a combination SGLT2i, GLP-1 RA, and nonsteroidal MRA has the potential to improve survival in patients with type 2 diabetes and at least moderately increased albuminuria.

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