Use of Multiple Control Tissue Types Recommended for Molecular Studies of Cerebrovascular Diseases

3d rendered medically accurate illustration of the head anatomy

Researchers at Brigham and Women’s Hospital determined the middle cerebral artery, circle of Willis, and paired superficial temporal artery (STA) are all feasible control vessels for transcriptomic studies of cerebrovascular diseases.


Bivalirudin As Efficacious As Heparin During PCI in NSTEMI and Has Better Safety Profile

Brigham and Women’s Hospital researchers conducted a patient-level meta-analysis of ACUITY plus four other large randomized trials. Bivalirudin was not associated with any significant difference in 30-day effectiveness outcomes compared with heparin, but had a substantially better safety profile.


Comprehensive Study Categorizes Economic Consequences of Stroke on the Global, Regional and Country Levels

Researchers at Brigham and Women’s Hospital recently completed the first study that assessed the macroeconomic consequences of stroke and its subtypes globally in a standardized way.


New TIMI Risk Score Provides Individualized CV Risk Profile for Patients With Type 2 Diabetes

Using contemporary data sets reflecting current clinical practices, researchers at Brigham and Women’s Hospital developed the TIMI Risk Score for Atherothrombosis in Diabetes, which uses information readily available from the medical chart to predict atherothrombotic complications in patients with type 2 diabetes.


Brigham Heart & Vascular Faculty at AHA Scientific Sessions 2023

Audience Full of People in Dark Conference Hall Watching Keynote Presentation

On November 11—13, 2023, experts from the Brigham’s Heart and Vascular Center will join thousands of colleagues in raising awareness and improving cardiovascular health at this year’s American Heart Association (AHA) Scientific Sessions.


Brigham Presents at Transcatheter Cardiovascular Therapeutics 2023

Cardiovascular experts from Brigham and Women’s Hospital will present at this year’s Transcatheter Cardiovascular Therapeutics (TCT) Conference on interventional cardiology, held October 23–26 in San Francisco, CA.


Multiomics Approach Implicates Tissue Extracellular Vesicles in Atherosclerosis and Calcific Aortic Valve Stenosis

Using a novel method, Brigham and Women’s Hospital researchers completed the first comparative proteomics study of pathogenesis in calcified carotid arteries and aortic valves (AVs), identifying unique drivers of atherosclerosis versus AV stenosis and implicating extracellular vesicles in both diseases.


Case Study: Endobronchial Valve Placement in a Patient With an Incomplete Lobar Fissure

CT scan of lungs before and after endobronchial valve placement

A team at the Brigham’s Lung Center performed a complex, two-step procedure to place endobronchial valves in a 59-year-old woman who had hyperinflation of her lungs due to advanced COPD, combined with an incomplete lobar fissure. Interventional pulmonologist Majid Shafiq, MD, MPH, discusses this challenging case.


Celebrating the 100th Anniversary of Breakthrough in Management of Mitral Valve Disease

Claude Beck, Eliot Cutler, Samuel Levine sitting at desk looking at papers, doctors working as team

In 1923, Dr. Elliot C. Cutler conducted the world’s first successful mitral valvuloplasty at the Brigham (then Peter Bent Brigham Hospital). On October 20, 2023, the Brigham will mark this important milestone with an all-day CME event looking at past, present, and future approaches to managing mitral valve disease.


Treatment Benefits and Safety of Sacubitril/Valsartan Are Maintained Despite Early eGFR Decline

Brigham and Women’s Hospital researchers found moderate eGFR decline when transitioning from a renin–angiotensin system inhibitor (RASi) to SV was not consistently associated with adverse outcomes. In addition, long-term benefits of SV were retained in patients with HF across a broad range of initial eGFR declines.