Brigham’s Endocrinology Chief Reflects on Recent Successes

Ursula B. Kaiser, MD

Brigham and Women’s Hospital’s Division of Endocrinology, Diabetes and Hypertension cares for patients with a wide range of hormonal and other related disorders, including diabetes, hypertension and thyroid disease. Division Chief Ursula B. Kaiser, MD, recently discussed some of her group’s accomplishments and how the COVID-19 pandemic has affected physicians and other health care providers in the division.

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Some Obesity-Linked Diseases May Be Related to Cholesterol

close up of cellsObesity is linked to an increased risk of many diseases, but much remains unknown about the molecular mechanisms underlying this connection. In a new study from Brigham and Women’s Hospital and Harvard Medical School, investigators have found an unexpected role for cholesterol and its effects on the immune system in driving some of these obesity-linked diseases — in particular, with conditions characterized by autoimmunity.

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Study Finds RA not Associated With Increased Type 2 DM Risk

Person doing finger prick for diabetesDoes rheumatoid arthritis (RA) raise the risk of developing type 2 diabetes mellitus (DM)? Previous epidemiologic studies have drawn varying conclusions. Now, a large population-based cohort study bolsters the case that RA in fact is not associated with a heightened risk.

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Neuroendocrine Collaboration Focuses on Cushing’s Disease

brain imaging

Cushing’s disease, caused by a pituitary adenoma, is the most common type of endogenous excessive cortisol production and results in Cushing’s syndrome. This is a particularly challenging disease to diagnose and treat. Surgery to remove the pituitary tumors that drive the disease can bring it under control, but these tumors can’t always be completely removed. In addition, they frequently recur, even a decade or more after surgery.

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Effort Aims to Bring Diabetes Care to Latinx Community

Woman playing with child

Latinx people are almost twice as likely to be diagnosed with type 2 diabetes as non-Hispanic whites, according to the American Diabetes Association. As part of its larger goal of addressing health care disparities in minority populations, Brigham and Women’s Hospital has begun efforts to advance systems of care, research and community programs that elevate the health status of communities in the Boston area, including the Latinx community.

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ED Diabetes Rapid-Referral Program Leads to Improved Mortality and Other Benefits

Picture a woman with acute diabetes arriving at the emergency department at 2 a.m. Her blood glucose level is extremely high and she is experiencing chest pain. Upon ruling out a heart attack and seeing no sign of hyperglycemic crisis, the ED physician concludes the patient does not require acute care. He then pages the doctor on call to request that outpatient care be arranged.

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Focusing on the Unique Health Care Needs of Transgender Individuals

transgender symbol

While social awareness and inclusion of the transgender population is on the rise, many transgender individuals continue to struggle in accessing and obtaining high-quality health care.

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Building on the Brigham’s Legacy of Leadership to Advance Adrenal Care

Team of doctors

Through its comprehensive clinical services and research efforts, the Center for Adrenal Disorders at Brigham and Women’s Hospital is playing a key role in advancing adrenal care. As such, it continues the institution’s long tradition of excellence in the field.

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Preserving Fertility with Minimally Invasive Myomectomy

3D illustration of surgical robot on white background

Uterine fibroids are highly prevalent in women over 35. As more women delay childbearing, techniques to remove uterine fibroids (leiomyomas) while also preserving fertility are of increasing importance.

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Exploring Sex Disparity in Coronary Microvascular Function Among T2D Patients

3d rendering red blood cells in vein

Women who have type 2 diabetes (T2D) without cardiovascular disease have impaired coronary flow reserve (CFR) compared to men. CFR—the ratio of stimulated to rest myocardial blood flow (MBF) assessed by cardiac PET—is a well-established indicator of coronary microvascular dysfunction and predictor of death.

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