Case Report: Recurrent Intraventricular Hemorrhage in Cerebral Proliferative Angiopathy With Very Long-term Follow-up

Cerebral proliferative angiopathy (CPA) is a cerebral vascular malformation with distinctive features. Brigham and Women’s Hospital researchers present one of the few reports of long-term follow-up of a patient with hemorrhage in CPA: 32 years of data on a patient who had recurrent hemorrhage.

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Artificial Intelligence, Machine Learning, and the Future of Neurosurgical Care

Timothy Smith, MD, PhD, MPH, a neurosurgeon-scientist in the Brigham’s Department of Neurosurgery, is exploring how to utilize artificial intelligence and machine learning to optimize neurosurgical patient care. He is co-author of three papers that offer a glimpse into how these technologies are transforming the field.

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Neuroimaging Abnormalities Across Substance Use Disorders Map to a Common Brain Network

Researchers have found that multiple substance use disorders (SUDs) map to their own common brain network, a finding that has therapeutic implications of its own.

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Gene Therapy Approach Shows Encouraging Survival Results in Some Patients With Glioblastoma

In a first-in-human, phase 1 trial, Brigham researchers sought to address challenges associated with treating glioblastoma multiforme by using an injected, engineered oncolytic virus that activated immune cells in the tumor. E. Antonio Chiocca, MD, PhD, senior author of the paper, recently presented the study findings.

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Review: Dural and Extradural Cavernous Venous Malformations

Neurologist and Neurosurgeon Talk, Use Computer, Analyse Patient MRI Scan, Diagnose Brain. Brain Surgery Health Clinic Lab: Two Professional Physicians Look at CT Scan. Close-up

In a two-part article in the Journal of Neurosurgery, surgeons at Brigham and Women’s Hospital discuss the epidemiology, clinical and radiologic features and surgical management of this group of pathologies. This summary covers part 1, dural and extradural CavVMs.

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SocialBit: A Wearable Sensor to Quantify Social Isolation

Researchers at Brigham and Women’s Hospital have developed SocialBit, a smartwatch-based sensor designed to track the number and duration of daily interactions of the person wearing it.

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Case Reports: Novel Congenital Spinal Cord Malformation Not Requiring Neurosurgery

Double face. Split personality. Mood disorder. 2 Head silhouette.Psychology. Dual personality.

Physicians at Brigham and Women’s Hospital have encountered two newborn infants with a novel syndrome they believe arises from errors in notochord formation. They report its clinical and radiographic characteristics, describe their treatment approach and theorize about the embryogenesis of the malformation.

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Use of Multiple Control Tissue Types Recommended for Molecular Studies of Cerebrovascular Diseases

3d rendered medically accurate illustration of the head anatomy

Researchers at Brigham and Women’s Hospital determined the middle cerebral artery, circle of Willis, and paired superficial temporal artery (STA) are all feasible control vessels for transcriptomic studies of cerebrovascular diseases.

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Blood Tests May Identify Which Patients With Stable MS Can Discontinue Treatment

close up picture of dripping liquid from pipette into test tube

Serum biomarkers are becoming increasingly investigated for risk profiling in MS. Researchers at Brigham and Women’s Hospital have found that changes in two of them after treatment is stopped can signal impending disease activity.

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Parkinson’s Disease Therapies: Genomic Insights and Stem-Cell Innovations

Clinicians and clinician-investigators in the Division of Movement Disorders in the Department of Neurology at Brigham and Women’s Hospital are taking various approaches to provide specialty care for patients facing a broad range of diseases that affect movement, including Parkinson’s disease.

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