Crossing Barriers in CNS Repair: Dr. Fengfeng Bei on Neural Regeneration and Gene Therapy

About one-third of epilepsy patients have a disease that is considered drug-resistant, meaning they have failed at least two medications. For these individuals, neurosurgical procedures offer the best chance of bringing their disease under control. Remarkably, the average time it takes for someone with…

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Improving Outcomes for Patients With Drug-resistant Epilepsy Through Surgery

Although current surgical approaches for treating drug-resistant epilepsy are already good, researchers at the Brigham are focused on developing treatments that are even more effective and less invasive. John David Rolston, MD, PhD, director of Epilepsy Surgery, highlights some of these promising efforts.

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Novel Polygenic Risk Score Validated for Aortic Stenosis

Researchers at Brigham and Women’s Hospital developed a novel aortic stenosis polygenic risk score (PRS) that incorporates more than five million genetic variants. They verified it was associated with aortic stenosis in two independent, very large populations.

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Mock Code Program Goes Beyond CPR to Test Brigham’s Emergency Response Systems

The Brigham and Women’s Hospital mock code program plans and conducts high-fidelity in situ simulations that not only allow participants to practice critical resuscitations but also test hospital systems for emergency response. Paul Jansson, MD, MS, and Andrew Eyre, MD, MS, elaborate on what distinguishes the program.

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Nasal Tuft Cells Direct the Olfactory Mucosal Response to Allergens

Researchers at Brigham and Women’s Hospital report that TRPM5+ MVCs in the olfactory neuroepithelium not only are tuft cells but also have a role beyond triggering inflammation: they regulate olfactory stem cell proliferation.

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Certain Blood Markers Linked to Premature Coronary Events in U.S. Women

By reviewing data from a long-term prospective study of U.S. women, researchers at Brigham and Women’s Hospital identified 12 biomarkers associated with premature CHD. They discuss the potential implications of biomarker screening and therapeutic strategies.

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Commentary: Equitable Abortion Care for Patients With Non-English Language Preference

In this commentary, Brigham and Women’s Hospital physicians draw on their knowledge of drivers of language-related inequities to suggest best clinical practices for patients with language barriers who need abortion care. They propose ways to advance abortion equity at the clinician, health system, and societal levels.

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