Latest Clinical & Research News
Giovanni Traverso, MD, PhD, MBBCH, of Brigham and Women’s Hospital and MIT, and colleagues have incorporated CO into gas-entrapping materials (GEMs) that can be delivered safely to the digestive tract.
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Ameya Kirtane, PhD, and Giovanni Traverso MD, PhD, MBBCH, and colleagues have developed oleogels—gels made from food-based oils—that can be used to deliver drugs to children. They report oleogels may perform similarly to or better than commercial tablets.
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Guo-Ping Shi, ScD, in the Department of Medicine at Brigham and Women’s Hospital, and colleagues review how allergic asthma affects the risk of cardiovascular disease.
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Advances in telemedicine are enabling the Brigham to bring high-quality neurosurgical care to patients nationally and internationally. Timothy R. Smith, MD, PhD, MPH, of the Department of Neurosurgery, discusses how these efforts reflect the broader movement to meet patients’ right to healthcare globally.
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Researchers at Brigham and Women’s Hospital recently completed the first large multicenter study of the incidence of ST-segment–elevation myocardial infarction (STEMI) as a complication of COVID-19. STEMI was rare in 0.35% of patients but was associated with poor in-hospital outcomes and high mortality.
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A potential cardiovascular benefit of vupanorsen would best be reflected by its effects on non–high-density lipoprotein cholesterol (non–HDL-C) and apolipoprotein B (ApoB). Brigham researchers studied vupanorsen at higher doses and observed significant reductions in non–HDL-C at all doses studied.
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In a post hoc analysis of the PARAGON-HF trial, Scott D. Solomon, MD, of the Division of Cardiovascular Medicine at Brigham and Women’s Hospital, and colleagues evaluated how atrial fibrillation and atrial flutter affected the results.
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Surgeons in the Department of Orthopaedic Surgery at Brigham and Women’s Hospital recently reviewed the evidence for and against pronator quadratus (PQ) muscle repair.
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A groundbreaking intranasal vaccine for Alzheimer’s disease (AD) developed at Brigham shows tremendous promise in its first phase of human trials. Study leader Howard L. Weiner, MD, discusses the trial’s progress to date, planned future phases, and how the vaccine could shape the future of AD care.
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The REDUCE-IT trial found patients at risk had reduced important ischemic events with icosapent ethyl. Prakriti Gaba, MD, and Deepak L. Bhatt, MD, MPH, of Brigham and Women’s Hospital, and colleagues, conducted a post hoc analysis limited to patients in the trial who had a history of myocardial infarction (MI).
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