Case Reports: Novel Congenital Spinal Cord Malformation Not Requiring Neurosurgery

Double face. Split personality. Mood disorder. 2 Head silhouette.Psychology. Dual personality.

Physicians at Brigham and Women’s Hospital have encountered two newborn infants with a novel syndrome they believe arises from errors in notochord formation. They report its clinical and radiographic characteristics, describe their treatment approach and theorize about the embryogenesis of the malformation.


Use of Multiple Control Tissue Types Recommended for Molecular Studies of Cerebrovascular Diseases

3d rendered medically accurate illustration of the head anatomy

Researchers at Brigham and Women’s Hospital determined the middle cerebral artery, circle of Willis, and paired superficial temporal artery (STA) are all feasible control vessels for transcriptomic studies of cerebrovascular diseases.


Blood Tests May Identify Which Patients With Stable MS Can Discontinue Treatment

close up picture of dripping liquid from pipette into test tube

Serum biomarkers are becoming increasingly investigated for risk profiling in MS. Researchers at Brigham and Women’s Hospital have found that changes in two of them after treatment is stopped can signal impending disease activity.


Bivalirudin As Efficacious As Heparin During PCI in NSTEMI and Has Better Safety Profile

Brigham and Women’s Hospital researchers conducted a patient-level meta-analysis of ACUITY plus four other large randomized trials. Bivalirudin was not associated with any significant difference in 30-day effectiveness outcomes compared with heparin, but had a substantially better safety profile.


New Study Highlights Dangers of Patients Relying on ChatGPT for Treatment Recommendations

Danielle S. Bitterman, MD, is the corresponding author of a study that assessed the ability of ChatGPT to recommend guidelines-based cancer treatments. She and her colleagues found the chatbot provided inappropriate recommendations in about one-third of cases, indicating the need to raise awareness about its limitations.


Parkinson’s Disease Therapies: Genomic Insights and Stem-Cell Innovations

Clinicians and clinician-investigators in the Division of Movement Disorders in the Department of Neurology at Brigham and Women’s Hospital are taking various approaches to provide specialty care for patients facing a broad range of diseases that affect movement, including Parkinson’s disease.


Comprehensive Study Categorizes Economic Consequences of Stroke on the Global, Regional and Country Levels

Researchers at Brigham and Women’s Hospital recently completed the first study that assessed the macroeconomic consequences of stroke and its subtypes globally in a standardized way.


Meet Adam Kibel, MD, Newly Appointed Chair of the Department of Urology

Meet Adam Kibel, MD, the newly appointed chair of the new Department of Urology at Brigham and Women’s Hospital and Disease Center Leader, Urology at Dana-Farber Brigham Cancer Center.


High BMI Portends Increased Risk for Certain Bariatric Procedures

Illustrations of Roux-en-Y Gastric Bypass and Sleeve Gastrectomy on white background

Brigham researchers presented the results of a study that aimed to stratify the risks of bariatric surgery at the American College of Surgeons’ Clinical Congress 2023. Ali Tavakkoli, MD, who led the study, explains the risk profile of bariatric procedures is changing as surgeons operate on heavier and heavier patients.


Brigham Establishes Department of Urology, Appoints Adam Kibel, MD, as Inaugural Chair

On October 1, 2023, Brigham and Women’s Hospital elevated its Division of Urology to a Department of Urology—the Brigham’s first new clinical and academic department in a decade. Adam S. Kibel, MD, was appointed chair of the newly established Department.