Persistent Tinnitus Linked to Individual Metabolites and Metabolite Classes for the First Time

Metabolite levels reflect an individual’s diet, environment, and gut microbiome, and researchers at Brigham and Women’s Hospital recently became the first to find associations between plasma metabolomic profiles and persistent tinnitus.


Using Video Interpretation to Enhance Care for Patients With Limited English Proficiency

Doctor and patient look at tablet, smiling; video interpretation in medical setting

Regan W. Bergmark, MD, a sinus and endoscopic skull base surgeon, is co-leading a project to advance language-concordant care in otolaryngology-head and neck surgery across the Mass General Brigham system. The team is trialing a mobile app that provides patients and physicians with live video interpretation on demand.


Proof of Concept: Olfactory Function Visualized With EEG Plus Magnetoencephalography/MRI

In a proof-of-concept study, Stella E. Lee, MD, director of the Sinus Center in the Division of Otolaryngology–Head & Neck Surgery at Brigham and Women’s Hospital, and colleagues demonstrated a safe, portable, objective method for measuring smell function and its relationship with cognitive processing.


Case Report: Hypertrophic Cardiomyopathy As an Unexpected Mimic of Inducible Laryngeal Obstruction

Close up of older man touching throat, discomfort, inducible laryngeal obstruction concept

Physicians at Brigham and Women’s Hospital recently encountered a patient with exertional dyspnea and inducible laryngeal obstruction at rest who was ultimately diagnosed with hypertrophic cardiomyopathy as the cause of his symptoms.


Initial Experience Supports Use of Silk–Hyaluronic Acid for Vocal Fold Injection Augmentation

The vocal folds

Christopher D. Dwyer, MD, Thomas L. Carroll, MD, and colleagues present the first publication to describe the use of Silk–HA (Silk Voice) for augmenting vocal fold tissue for phonation improvement in patients, including clinical pearls and suggestions for the informed consent process.


New International Classification of Laryngopharyngeal Reflux Considers Quality of Life

3D illustration of human larynx and pharynx anatomy, laryngopharyngeal reflux concept

Thomas L. Carroll, MD, director of the Voice Program at Brigham and Women’s Hospital, and colleagues have developed the first classification of laryngopharyngeal reflux severity that stratifies patients based on the impact of their symptoms on quality of life.


Biologic Therapies Shifting the Paradigm for Treating Chronic Rhinosinusitis

CT scan of patient after dupilumab treatment for chronic rhinosinusitis

For years, patients with chronic rhinosinusitis (CRS) and nasal polyps had few treatment options beyond topical corticosteroids and surgery. Stella Lee, MD, director of the Brigham Sinus Center, conducted trials of three biologic therapies showing signs of addressing CRS symptoms and improving patient quality of life.


Angled Fiber Tips Improve Anatomic Access in Models of In-Office Laser Treatment of the Larynx

3D rendering of larynx anatomy in throat of human being, highlighted orange

In two high-definition larynx models, Chan and colleagues recently demonstrated that side-firing laser fibers may substantially increase endoscopic access to difficult lesions. Now, researchers at Brigham and Women’s Hospital have built on that work, corroborating the results in additional, more varied anatomic models.


Delphi Process Determines Best Practices for Laryngopharyngeal Reflux Disease Treatment

Woman standing holding chest highlighted in red for laryngopharyngeal reflux disease discomfort

Thomas L. Carroll, MD, section chief of Laryngology and director of the Voice Program at Brigham and Women’s Hospital, and colleagues recently completed a Delphi process to develop guidance about treating laryngopharyngeal reflux disease (LPR). They report their consensus.


VESPA Scale Identifies Head and Neck Surgical Patients at Risk for Delayed or Complex Discharge

Empty hospital bed for recovery after surgery with heart monitor, wheelchair

Ashley L. Miller, MD, a resident in the Division of Otolaryngology–Head and Neck Surgery at Brigham and Women’s Hospital, and colleagues demonstrated that VESPA can identify patients scheduled for major otolaryngologic head and neck surgery who are at risk of delayed or complex discharge.