Researchers at Brigham and Women’s Hospital report that TRPM5+ MVCs in the olfactory neuroepithelium not only are tuft cells but also have a role beyond triggering inflammation: they regulate olfactory stem cell proliferation.

Mass General Brigham researchers recently completed the first human study that examined links between metabolites and persistent tinnitus. They say metabolomic profiling is a promising approach to pinpointing tinnitus biomarkers and should provide valuable insights into the pathophysiology of the disorder.

C. Eduardo Corrales, MD, at Brigham and Women’s Hospital, Nir Ben-Shlomo, MD, of the University of Iowa Hospitals and Clinics, and colleagues recently undertook two related studies and present suggestions for avoiding iatrogenic inner ear dehiscence (IED) complications after surgery.

A systematic review recommends that any core set of measurement tools for adductor laryngeal dystonia (AdLD) should include three domains: perceptual measures, acoustic measures, and patient-reported outcome measures (PROMs).

Metabolite levels reflect an individual’s diet, environment, and gut microbiome, and researchers at Brigham and Women’s Hospital recently became the first to find associations between plasma metabolomic profiles and persistent tinnitus.

Regan W. Bergmark, MD, a sinus and endoscopic skull base surgeon, is co-leading a project to advance language-concordant care in otolaryngology-head and neck surgery across the Mass General Brigham system. The team is trialing a mobile app that provides patients and physicians with live video interpretation on demand.

In a proof-of-concept study, Stella E. Lee, MD, director of the Sinus Center in the Division of Otolaryngology–Head & Neck Surgery at Brigham and Women’s Hospital, and colleagues demonstrated a safe, portable, objective method for measuring smell function and its relationship with cognitive processing.

Christopher D. Dwyer, MD, Thomas L. Carroll, MD, and colleagues present the first publication to describe the use of Silk–HA (Silk Voice) for augmenting vocal fold tissue for phonation improvement in patients, including clinical pearls and suggestions for the informed consent process.