Certain Plasma Metabolites and Metabolite Classes Linked to Persistent Tinnitus

Mass General Brigham researchers recently completed the first human study that examined links between metabolites and persistent tinnitus. They say metabolomic profiling is a promising approach to pinpointing tinnitus biomarkers and should provide valuable insights into the pathophysiology of the disorder.


Improving Outcomes in Skull Base Surgery: Avoiding Inner Ear Breaches During Lateral Skull Base Surgery

C. Eduardo Corrales, MD, at Brigham and Women’s Hospital, Nir Ben-Shlomo, MD, of the University of Iowa Hospitals and Clinics, and colleagues recently undertook two related studies and present suggestions for avoiding iatrogenic inner ear dehiscence (IED) complications after surgery.


Subjective, Objective and Patient-rated Outcomes of Adductor Laryngeal Dystonia Treatment Rarely Correlate

A systematic review recommends that any core set of measurement tools for adductor laryngeal dystonia (AdLD) should include three domains: perceptual measures, acoustic measures, and patient-reported outcome measures (PROMs).


International Consensus: Definition and Diagnostic Criteria for Laryngopharyngeal Reflux

A multidisciplinary group of experts developed a consensus document about the definition and diagnosis of laryngopharyngeal reflux (LPR). It’s been named the Dubai Definition and Diagnostic Criteria of LPR after the conference’s location where it was first presented.


Persistent Tinnitus Linked to Individual Metabolites and Metabolite Classes for the First Time

Metabolite levels reflect an individual’s diet, environment, and gut microbiome, and researchers at Brigham and Women’s Hospital recently became the first to find associations between plasma metabolomic profiles and persistent tinnitus.


Using Video Interpretation to Enhance Care for Patients With Limited English Proficiency

Doctor and patient look at tablet, smiling; video interpretation in medical setting

Regan W. Bergmark, MD, a sinus and endoscopic skull base surgeon, is co-leading a project to advance language-concordant care in otolaryngology-head and neck surgery across the Mass General Brigham system. The team is trialing a mobile app that provides patients and physicians with live video interpretation on demand.


Proof of Concept: Olfactory Function Visualized With EEG Plus Magnetoencephalography/MRI

In a proof-of-concept study, Stella E. Lee, MD, director of the Sinus Center in the Division of Otolaryngology–Head & Neck Surgery at Brigham and Women’s Hospital, and colleagues demonstrated a safe, portable, objective method for measuring smell function and its relationship with cognitive processing.


Case Report: Hypertrophic Cardiomyopathy As an Unexpected Mimic of Inducible Laryngeal Obstruction

Close up of older man touching throat, discomfort, inducible laryngeal obstruction concept

Physicians at Brigham and Women’s Hospital recently encountered a patient with exertional dyspnea and inducible laryngeal obstruction at rest who was ultimately diagnosed with hypertrophic cardiomyopathy as the cause of his symptoms.


Initial Experience Supports Use of Silk–Hyaluronic Acid for Vocal Fold Injection Augmentation

The vocal folds

Christopher D. Dwyer, MD, Thomas L. Carroll, MD, and colleagues present the first publication to describe the use of Silk–HA (Silk Voice) for augmenting vocal fold tissue for phonation improvement in patients, including clinical pearls and suggestions for the informed consent process.


New International Classification of Laryngopharyngeal Reflux Considers Quality of Life

3D illustration of human larynx and pharynx anatomy, laryngopharyngeal reflux concept

Thomas L. Carroll, MD, director of the Voice Program at Brigham and Women’s Hospital, and colleagues have developed the first classification of laryngopharyngeal reflux severity that stratifies patients based on the impact of their symptoms on quality of life.