Semaglutide Lowers Risk of COVID Death
Research has found that people taking GLP-1 weight-loss drugs had significantly lower risk of death from COVID-19 and other infectious and cardiovascular causes.
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COVID-19 News
Patterns and Disparities in Telehealth Usage Across Surgical Specialties During the COVID-19 Pandemic
Quoc-Dien Trinh, MD, MBA, of the Department of Urology, and colleagues found that the usage of telehealth varied by surgical specialty during the COVD-19 pandemic, and their findings support previous data on socioeconomic disparities in telemedicine uptake.
Read More...Risk Factors Identified for Repeat COVID-19 in Patients With Systemic Autoimmune Rheumatic Diseases
Jeffrey Sparks, MD, MMSc, and colleagues recently completed the first study of risk factors for repeat COVID-19 in an immunocompromised population. They report that use of rituximab, use of methotrexate, and younger age increased the risk of repeat COVID-19 among patients with systemic autoimmune rheumatic diseases.
Read More...Nasal Monoclonal Antibody Suppresses Inflammatory Response in COVID-19
In a new study, a Brigham team determined how nasal foralumab modulates inflammation and describes a potential novel avenue for treating not just COVID-19 but also autoimmune diseases.
Read More...Paxlovid Reduces COVID-19 Hospitalization Among Vaccinated Older Adults
A Mass General Brigham study suggests nirmatrelvir plus ritonavir (Paxlovid) reduces COVID-19 severity even in highly vaccinated adults over the age of 50. In this Q&A, Scott Dryden-Peterson, MD, MSc, and Ann Woolley, MD, MPH, discuss key takeaways from the study and describe best methods for prescribing Paxlovid.
Read More...Relative Hyperglycemia Is a Marker of Disease Severity in COVID-19
The “glycemic gap” has previously been validated as a predictor of severe acute illness. Now, Brigham and Women’s Hospital researchers have extended the glycemic index’s utility to COVID-19.
Read More...Meta-analysis: Stroke Response Times Early in COVID-19 Depended on Metric, Type of Center
Delays in stroke treatment were inevitable during the early months of the COVID-19 epidemic, given virus-related precautions and the massive influx of COVID-19 patients into hospitals. Understanding the precise extent of those delays is important to learn what factors lead to late care.
Read More...Prospective RCT Finds Full-Dose Anticoagulation Better Than Standard Dose in Severe COVID-19
In COVID-PACT, a 2×2 factorial, randomized, controlled trial that enrolled critically ill patients with COVID-19, researchers at Brigham and Women’s Hospital determined full-dose anticoagulation was superior to standard-dose prophylaxis in reducing the proportion of patients experiencing a thrombotic event.
Read More...Brigham Researchers Create COVID-19 Genome Catalog of the Human Microbiome
Researchers at Brigham and Women’s Hospital analyzed whole-metagenome shotgun (WMS) sequencing data by reconstructing microbial population genomes directly from microbiome samples of COVID-19 patients and controls. They report the creation of the first high-quality COVID-19–related genome catalog of the gut microbiome.
Read More...STEMI Rare in Patients Hospitalized With COVID-19, but Prognosis Is Poor
Researchers at Brigham and Women’s Hospital recently completed the first large multicenter study of the incidence of ST-segment–elevation myocardial infarction (STEMI) as a complication of COVID-19. STEMI was rare in 0.35% of patients but was associated with poor in-hospital outcomes and high mortality.
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