Presurgical Physical, Psychosocial and Sensory Factors All Influence Total Knee Arthroplasty Outcomes

Doctor evaluates patient knee suture scar after total knee arthroplasty

Robert R. Edwards, PhD, of the Center for Pain Management at Brigham and Women’s Hospital, and colleagues conducted the first multicenter study that comprehensively examined clinical, functional, psychosocial and sensory factors as predictors of pain and functional outcomes after total knee arthroplasty.

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Inside the NICU: When the Parent Becomes the Patient

Close up of doctor's hands holding a newborn in the NICU

The Brigham’s new multidisciplinary Parent Mental Health Program, created by Cindy H. Liu, PhD, and Leena P. Mittal, MD, is designed to provide timely and consistent mental health services for parents and caregivers of infants hospitalized in the neonatal intensive care unit.

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22q11.2 Deletion, Duplication Linked to Opposing Changes in White Matter

3D color medical concept of human brain white matter

Ofer Pasternak, PhD, and Johanna Seitz-Holland, MD, PhD, of the Department of Psychiatry at Brigham and Women’s Hospital, and colleagues conducted the first study to compare white matter in 22q-del and 22q-dup, and report finding opposing abnormalities that might indicate distinct pathologies.

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How Trauma-informed Care Improves the Patient Experience

Robert Wood Johnson Foundation Clinical Scholars Program Team

In the past two years, the COVID-19 pandemic and a renewed emphasis on issues surrounding racial justice have brought the need for trauma-informed healthcare into greater focus. Consultation-liaison psychiatrist Nomi Levy-Carrick, MD, MPhil, has been involved in expanding such programs across more areas of the Brigham.

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Brain Circuit Mapping Refines Targets for Neurostimulation

Researchers at Brigham and Women’s Hospital have developed a novel brain mapping method that suggests lesions, TMS and DBS converge on a common brain circuit for depression—which may represent a better target for therapeutic neurostimulation. The approach seems to be generalizable to other neuropsychiatric diseases.

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Neural Circuit for Spirituality and Religiosity Identified

Human Brain Scan X-Rays

By using a newer technique called lesion network mapping, Michael Ferguson, PhD, Michael D. Fox, MD, PhD, of the Center for Brain Circuit Therapeutics at Brigham and Women’s Hospital, and colleagues have identified a specific brain circuit that seems to be a neural substrate for spirituality and religiosity.

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COVID-19–related Psychological Factors Can Interfere with Mother–Infant Bonding

Mother holds and looks down at newborn infant

In a nationwide online survey of pregnant and postpartum women, Cindy H. Liu, PhD, and Carmina Erdei, MD, of Brigham and Women’s Hospital, and colleagues determined that psychological factors related to COVID-19, particularly grief, pose unique hazards to mother–infant bonding.

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Targeting Common Causal Circuits With Brain Stimulation to Treat Depression

Can targeting certain brain circuits with therapeutic stimulation modulate neuropsychiatric symptoms? A recent study involving multiple Brigham and Women’s Hospital investigators including Michael D. Fox, MD, PhD, and Shan H. Siddiqi, MD, MBBS, answers that crucial question in the affirmative.

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Studying Pandemic’s Effect on Mental Health in Young Adults

Young adults in masks at schoolThe COVID-19 pandemic has been challenging for almost everyone, and different populations have been hit in different ways. For people aged 18–30 years, it has had an outsized effect on mental health, especially in terms of depression, anxiety and post-traumatic stress disorder (PTSD).

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Improving Telehealth in Psychiatry for Non-English Speakers

woman on phone at home

Telemedicine has become an increasingly important mode of care during the COVID-19 pandemic. Certain specialties lend themselves to telemedicine to a greater degree than others. One of these is psychiatry, thanks in large part to relevance of observation and conversation with patients and their families to obtain neuropsychiatric history.

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