Geographic Disparities Demonstrated in Outcomes After Orthopedic Trauma Surgery

Close up of person using crutches to walk with brace on ankle and leg, broken leg concept

It’s been established that unequal distribution of physicians contributes to overall healthcare disparities between urban and rural communities. Now, Brigham and Women’s Hospital researchers have demonstrated the same is true for orthopedic trauma outcomes.


Harvest Technique Affects the Quality of Osteochondral Grafts

Typical synovial joint showing the bone synovial membrane synovial fluid cartilage and ligament

Chondrocytes are quite fragile; even minor mechanical insults can result in substantial cell death and graft compromise. A Brigham study determined the optimal technique for harvesting the plugs and found both methods lead to significant mechanical injury at the edge of the explants compared with scalpel incision.


Assessing Impacts of Knee Osteoarthritis Solely With Patient Self-report May Miss Deficits

Older individual sitting on couch holding knee in pain, knee osteoarthritis concept

Researchers at Brigham and Women’s Hospital present additional evidence that both subjective and objective measures are of value in assessing functional status in patients with knee osteoarthritis.


Systematic Review: Effectiveness of Remote Exercise Programs for Pain Reduction in Knee Osteoarthritis

Woman stretching on yoga mat at home in front of laptop, remote exercise concept

In-person exercise programs are well-established to effectively reduce pain in patients with knee osteoarthritis (OA). Elena Losina, PhD, and colleagues recently explored whether the same is true of remote exercise programs.


Severe Obesity Linked to Worse Outcomes, Higher Costs of Lower Extremity Fracture Surgery

Obese female patient consulting with male doctor in white coat, looking at clipboard

Michael J. Weaver, MD, and colleagues recently became the first to project the cost implications of severe obesity for treating lower extremity fractures, along with studying its effect on complications and healthcare utilization.


Characteristics and Outcomes of Patients Who Undergo Fasciotomy for Acute Upper Arm Compartment Syndrome

Woman holding upper arm, ache and pain concept

Acute upper arm compartment syndrome is rare, and little has been published about it. Dafang Zhang, MD, of the Department of Orthopaedic Surgery at Brigham and Women’s Hospital, and colleagues recently described patient characteristics and outcomes.


Novel Antibiotic in Standard Bone Cement Implant Is Broadly Antimicrobial

Doctor examining a patient's ankle wrapped and highlight red, orthopedic surgery recovery concept

Researchers at Brigham and Women’s Hospital rationally designed a new antibiotic, VCD-077, to be physiochemically compatible with standard bone cement for local treatment of orthopedic infections with much less chance of resistance.


Polarization-Sensitive OCT Technically Feasible for Assessing Pre-Osteoarthritis

Female patient at ophthalmologist leaning toward machine for optical coherence tomography testing

Mass General Brigham clinicians and colleagues showed polarization-sensitive optical coherence tomography (PS-OCT) can be performed minimally invasively and report results from a pilot study that will inform a large clinical trial to determine whether PS-OCT can predict the development of osteoarthritis.


CRP-to-Albumin Ratio Reflects Risk of Adverse Events After Spinal Epidural Abscess Treatment

MRI of cervical spine showing epidural abscess that causes spinal cord compression and paralysis

Matthew H. Lindsey, MD, Andrew J. Schoenfeld, MD, MSc, of the Department of Orthopaedic Surgery at Brigham and Women’s Hospital, and colleagues have published putative evidence that the C-reactive protein to albumin ratio can help predict adverse events after spinal epidural abscess treatment.


Cost of Anterior Cervical Decompression and Fusion Are Highly Variable in Healthcare Systems

Lateral projection cervical spine x-ray showing anterior cervical discectomy and fusion or ACDF procedure.

Hospital costs associated with anterior cervical decompression and fusion (ACDF) are highly heterogeneous. Andrew K. Simpson, MD, MBA, MHS, the Department of Orthopaedic Surgery at Brigham and Women’s Hospital, and colleagues conducted the first rigorous analysis of the relative drivers of ACDF costs.