Brigham’s Otolaryngology Division Grows in Line With Mission


The Division of Otolaryngology-Head and Neck Surgery at Brigham and Women’s Hospital offers expert, individualized care for a range of conditions affecting the ear, nose and throat. Since 2017, Ravindra Uppaluri, MD, PhD, has served as the division chief for the group’s multidisciplinary faculty and staff.

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Reducing Treatment Toxicity in Head and Neck Cancer

robot close up

A Phase 2 trial run by the Adult Head and Neck Oncology Program at Dana-Farber/Brigham and Women’s Cancer Center (DF/BWCC) is seeking to reduce the side effects of postoperative therapy for certain head and neck cancer patients, helping them have a better quality of life while maintaining cancer cure rates.

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Making the Case Against Using Intranasal Steroids and Antihistamines for Otitis Media With Effusion


illustration of eustachian tubeShould allergy medications such as intranasal steroids and oral antihistamines be used to treat isolated otitis media with effusion (OME)? The answer is a resounding no, according to a review of previously collected data published in October’s Current Allergy and Asthma Reports. Rachel E. Roditi, MD, of the Brigham and Women’s Hospital Division of Otolaryngology-Head and Neck Surgery is lead author of the paper.

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New Skull Base Surgery Technology Designed to Eliminate Postsurgical Complications

Illustration of organs

A duo at Brigham and Women’s Hospital has developed a new intraoperative, image-based guidance system to help surgeons more accurately visualize anatomical structures. The technology uses augmented reality to precisely register operative endoscopy views with preoperative CT or MRI images, allowing for real-time adjustment and fine-tuning based on the operator’s changing visual field.

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Novel Hypoglossal Nerve Stimulation Procedure Helps Sleep Apnea Patients Breathe Easier

Man sleeping

Clinicians at Brigham and Women’s Hospital are using hypoglossal nerve stimulation (HNS) to treat obstructive sleep apnea (OSA) in patients who struggle to tolerate the first-line therapy, continuous positive airway pressure (CPAP). The Brigham is a leader in using the novel procedure, which involves surgically implanting a device in patients to relieve apnea episodes. HNS offers hope to those with OSA who are intolerant to CPAP.

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Maximizing Function in Full Face Transplant Recipients

In 2011, Brigham and Women’s Hospital made headlines as the site of the nation’s first full face transplant. In July 2019, the Brigham set another milestone with the world’s first full face transplant procedure on a black patient and the oldest recipient ever. It was the ninth face transplant at the Brigham and the 15th nationwide.
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Addressing Racial and Income Disparities in Oral Cancer Screening

Oral cancers account for about two percent of all malignancies and 1.2 percent of cancer-associated deaths. If oral cancer is caught early, the five-year survival rate is 82.8 percent. Once the cancer metastasizes, that rate drops to 28 percent.

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Cancer Moonshot Grant Supports Study of Head and Neck Cancer Immunotherapy Resistance

Image: Multiplex Immunofluorescence of Head and Neck Cancer samples, in collaboration with Scott J. Rodig, MD, PhD.

A collaborative research team at Dana-Farber/Brigham and Women’s Cancer Center (DF/BWCC) has received a grant to study immunotherapy resistance in head and neck cancer. The team is one of a handful to receive a multi-year cancer immunotherapy research grant this year from the National Institutes of Health (NIH) as part of the Cancer Moonshot program.

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Developing a Novel, Off-the-Shelf Vocal Cord Augmentation System

Silk-HA delivery deviceFor decades, the medical and scientific community has looked for ways to repair damaged vocal cords through injectable agents. Current best practices involve the use of carboxymethylcellulose, hyaluronic acid or calcium hydroxylapatite (CaHA). However, these injectable agents do not provide permanent effects and typically carry the additional burden of requiring two people to perform the medialization procedure, thus adding to their cost.
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Brigham Remains a Leader in Full and Partial Face Transplantation

2011, Boston, MA, USA, LIGHTCHASER PHOTOGRAPHY, Brigham and Women's Hospital Department of Plastic Surgery in coordination with the hospitals entire transplant team and the New England Organ Bank worked throughout an entire day to replace the soft facial tissues of Dallas Wiens, 25, from Dallas TX, who flew to Boston late at night for the procedure. The transplant team, led by Dr. Bohdan Pomahac, began their surgical procedures shorty after 3 a.m. and Dallas Wiens was transported to the BWH ICU shortly before 9 p.m. at night. ( lightchaser photography image by j. kiely jr. © 2011 )Face transplants are still infrequent enough that every one of them is considered a remarkable feat of medical collaboration and expertise. However, they no longer garner the news headlines that the first transplant did when it was performed in France in 2005.
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