Cancer Moonshot Grant Supports Study of Head and Neck Cancer Immunotherapy Resistance

Image: Multiplex Immunofluorescence of Head and Neck Cancer samples, in collaboration with Scott J. Rodig, MD, PhD.

A collaborative research team at Dana-Farber/Brigham and Women’s Cancer Center (DF/BWCC) has received a grant to study immunotherapy resistance in head and neck cancer. The team is one of a handful to receive a multi-year cancer immunotherapy research grant this year from the National Institutes of Health (NIH) as part of the Cancer Moonshot program.

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Developing a Novel, Off-the-Shelf Vocal Cord Augmentation System

Silk-HA delivery deviceFor decades, the medical and scientific community has looked for ways to repair damaged vocal cords through injectable agents. Current best practices involve the use of carboxymethylcellulose, hyaluronic acid or calcium hydroxylapatite (CaHA). However, these injectable agents do not provide permanent effects and typically carry the additional burden of requiring two people to perform the medialization procedure, thus adding to their cost.
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Brigham Remains a Leader in Full and Partial Face Transplantation

2011, Boston, MA, USA, LIGHTCHASER PHOTOGRAPHY, Brigham and Women's Hospital Department of Plastic Surgery in coordination with the hospitals entire transplant team and the New England Organ Bank worked throughout an entire day to replace the soft facial tissues of Dallas Wiens, 25, from Dallas TX, who flew to Boston late at night for the procedure. The transplant team, led by Dr. Bohdan Pomahac, began their surgical procedures shorty after 3 a.m. and Dallas Wiens was transported to the BWH ICU shortly before 9 p.m. at night. ( lightchaser photography image by j. kiely jr. © 2011 )Face transplants are still infrequent enough that every one of them is considered a remarkable feat of medical collaboration and expertise. However, they no longer garner the news headlines that the first transplant did when it was performed in France in 2005.
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Brigham Otolaryngologist Takes His Expertise to Haiti

Dr. Prince performing a procedure in Haiti.The expertise of the physicians and surgeons at Brigham and Women’s Hospital benefits patients well beyond New England. Through Partners in Health, the Boston-based nonprofit health care organization, specialists from the Brigham travel to hospitals in developing countries around the globe, offering patient care as well as training for local doctors.
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Link Between Hearing Problems and Accidental Injuries

Lund, Sweden - April 11, 2016: Real life in the city. Elderly woman is out walking, crossing a street with her walker. No traffic visible.

As the American population ages, a greater percentage of people will suffer from moderate to severe hearing loss. Research shows that older people also are at a higher risk of accidental injuries.

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Repairing Lateral Sphenoid Cerebrospinal Fluid Leaks Endoscopically

Cerebrospinalfluid (CSF) leaks in the lateral recess of the sphenoid (LRS) are rare. For cases in which they do occur, however, Brigham and Women’s Hospital offers a minimally invasive, endoscopic alternative to traditional open surgery.

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Periostin May Be a Novel Biomarker to Classify Patients with Chronic Rhinosinusitis

A recent study from the Division of Otolaryngology at Brigham and Women’s Hospital (BWH) showed that serum periostin, an extracellular matrix protein, may be a novel biomarker for the presence of nasal polyps in patients with chronic rhinosinusitis (CRS), and could potentially serve as a target for future therapeutic interventions. The findings were published in the October 2017 issue of Otolaryngology Head Neck SurgRead More