A meta-analysis of five clinical trials found that adding docetaxel to standard-of-care treatment in men with high-grade, nonmetastatic prostate cancer and low PSA levels was associated with a significant reduction in death from prostate cancer. The Brigham’s Anthony Victor D’Amico, MD, PhD, senior author of the new paper, elaborates.

Immunotherapy drugs that harness a patient’s immune system to fight cancer have become an important treatment for a subset of patients with certain cancers. A team co-led by investigators from Brigham and Women’s Hospital has uncovered new findings about why some patients fail to respond to these drugs. The research suggests new approaches for making the medications more effective. Read More

The efficacy of prostate-specific antigen (PSA) screening in reducing prostate cancer (PCa) mortality remains a matter of debate. Nonetheless, some racial and ethnic minority groups—particularly Black and Hispanic men—are less likely to receive prostate cancer screening and treatment. This discrepancy, in turn, may contribute to racial and ethnic disparities in PCa outcomes, including higher mortality rates. Read More

Immune-checkpoint blockade (ICB) therapy has been a life-changing advance for a subset of people with cancer, but additional research is needed to learn how to make these treatments more broadly effective and longer lasting. A team led by scientists at Brigham and Women’s Hospital has published a paper revealing new details about the tumor characteristics that facilitate a strong clinical response to these drugs. Read More

The 2023 ASTRO Annual Meeting – the leading meeting in radiation oncology is holding its annual conference October 1-4. Several leaders from Brigham and Women’s Hospital/Dana-Farber Brigham Cancer Center will present their latest research and clinical advancements in their particular areas of expertise in radiation oncology. Read More