Clinic Screens High-Risk Patients to Reduce Incidence of Anal Cancer

HSIL pathology slide

A Brigham clinic offers high-resolution anoscopy to screen for anal dysplasia in people at increased risk of anal cancer due to HPV infection, HIV status, and other factors. Co-founders James Yoo, MD, and Jennifer A. Johnson, MD, explain their mission to reduce the incidence of anal cancer in high-risk populations.


Economic Burden of Neuromyelitis Optica Spectrum Disorders Quantified From Patient Point of View

Brigham and Women’s Hospital researchers recently conducted the first study of patient-reported data on the economic burden of neuromyelitis optica spectrum disorders (NMOSD). Specifically, they characterized the direct and indirect costs of relapse events (ED visits and hospitalizations).


Brigham Team Discovers Mechanism of Th17 Cell Production in the Gut

Rendering of Interleukin 17, a cytokine produced by T-helper cells, on black background

Brigham and Women’s Hospital recently determined how epithelial cells promote Th17 cell generation in response to bacterial colonization as a step toward better understanding the treatment—and even prevention—of chronic inflammatory diseases.


Embedding Diabetes Care in the Latino Community

Headshot of A. Enrique Caballero, MD on gray background

The Brigham’s new approach to providing diabetes care for Latino/Hispanic patients involves embedding diabetes specialists in community clinics and offering culturally and linguistically appropriate services to help patients control their disease and its complications, as A. Enrique Caballero, MD, explains.


AAOS 2023: Andrew J. Schoenfeld, MD, Discusses the Cost-Utility Benefits of Robotic Assistance for Adult Spinal Deformity Procedures

In this video from the 2023 American Academy of Orthopaedic Surgeons Annual Meeting, Professor Andrew J. Schoenfeld, MD, describes his recent research on the cost-utility benefits of robotic assistance for adult spinal deformity procedures.


Variants of AAV9 Efficiently Cross the Blood–Brain Barrier in Non-Human Primates

Researchers at Brigham and Women’s Hospital have designed two promising AAV9 variants that are much more effective than the parent vector for delivering therapeutic transgenes into the central nervous system of mice and macaques.


People Have “Massive” Memory for Where and When They Saw Something

Researchers at Brigham and Women’s Hospital have shown more specifically that humans have a spatial massive memory—they can remember where they saw objects presented briefly—and a temporal massive memory—they can remember when they saw the objects.


New Online Tool Calculates Patient-specific “Safe Zones” for Acetabular Component Positioning During THA

3D illustration of pelvic bone and femur, with total hip arthroplasty installed

Researchers at Brigham and Women’s Hospital have created a quantitative tool that can be used for patient-specific preoperative planning and intraoperative adjustment of acetabular component position during total hip arthroplasty, with or without assistive intraoperative technology.


Progression of Interstitial Lung Disease Likely in Relatives of Patients With Pulmonary Fibrosis

Brigham researchers previously reported that first-degree relatives of patients with pulmonary fibrosis have high rates of interstitial lung abnormalities (ILA). Their two-year follow-up indicates radiologic progression of ILA was common in relatives and may be associated with accelerated loss of lung function.


Common Brain Network Identified for Multiple Psychiatric Disorders May Improve Neuromodulation

Researchers at Brigham and Women’s Hospital recently addressed neuroimaging research limitations. By coupling morphometric and brain lesion datasets with a “wiring” diagram of the brain, they derived a common brain network for psychiatric illness that is sensitive, specific, and robust.