High Prevalence of Parenchymal Lung Diseases in Patients With Rheumatoid Arthritis

CT scan of patient with emphysema in the lungs

Tracy J. Doyle, MD, Jeffrey A. Sparks, MD, MMSc, and colleagues identified a high prevalence of undiagnosed preclinical parenchymal lung disease in a rheumatoid arthritis cohort, with important clinical implications.


Esophagectomy Complication Rate Higher with Low-volume Surgeons Even at the Same High-volume Center

Close up of two surgeons beginning thoracic surgery

A study conducted by Daniel Dolan, MD, MPH, Scott J. Swanson, MD, of the Division of Thoracic Surgery, and colleagues determined that even at the Brigham’s high-volume center, low individual esophagectomy volume was associated with a higher perioperative complication rate.


Preoperative Risk Factors Identified for Prolonged Air Leaks Requiring Intervention

X-ray of patient with upper lung resection

Researchers at the Brigham, including Matthew M. Rochefort, MD, and Aaron R. Dezube, MD, of the Division of Thoracic and Cardiac Surgery, and colleagues retrospectively studied a large series of patients undergoing lung resection to determine the incidence of severe prolonged air leaks and its risk factors.


Sinonasal and Asthma Symptom Severities Correlated in Aspirin-exacerbated Respiratory Disease

Woman with asthma uses inhaler

Using prospectively collected registry data, researchers at Brigham and Women’s Hospital linked increased severity of sinonasal symptoms in patients with aspirin-exacerbated respiratory disease to both worse patient-reported asthma control and worse objectively measured lung function.


Pulmonary Microbiome May Identify Patients With High-risk Lymphangioleiomyomatosis

CT Scan of a patient with LAM

Souheil Y. El-Chemaly, MD, and Julie Ng, MD, of Brigham and Women’s Hospital, and colleagues conducted the first study to examine the lung microbiome of patients with lymphangioleiomyomatosis (LAM) who were at high risk of disease progression or death.


Active Lifestyle May Reduce Incidence of Obstructive Sleep Apnea

Yue Liu, MD, a research fellow at the Brigham, Tianyi Huang, ScD, an associate epidemiologist, and colleagues have linked physical inactivity and sedentary behavior with obstructive sleep apnea incidence, suggesting an active lifestyle may have a role in prevention.


Asthma Is Greatest Risk Factor for Early COPD in U.S. Latino/a/x Communities

Older Male Patient Uses Spirometry - Respiratory Test

Several studies in predominantly older white populations have identified various risk factors for early COPD such as asthma. Now, Fariha Khalid, MD, MPH, Alejandro A. Diaz, MD, MPH, of Brigham and Women’s Hospital and colleagues have conducted one of the largest studies of early COPD in U.S. Hispanics/Latinos.


Knocking Out Respiratory Viruses Before They Cause Damage

Brigham researchers are seeking to limit the severe effects of respiratory viruses by using new methods to reduce the viral load and excessive lung inflammation that are common with these lung infections. Pulmonologist Bruce D. Levy, MD, is a corresponding author of a recently published article on this research.


Image Intelligence Promotes Understanding and Treatment of Lung Disease


Lung diseases like chronic obstructive pulmonary disease (COPD) can be remarkably diverse in their pathologies and the ways in which patients respond to treatment. To better understand diseases such as COPD, pulmonary vascular disease and interstitial lung disease, researchers at Brigham and Women’s Hospital created the Applied Chest Imaging Laboratory (ACIL). The lab leverages the power of imaging and hypothesis-driven modeling to create algorithms that empower clinical and genetic research.

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Robotic Thoracic Surgery Extends Minimally Invasive Options to More Patients

Doctor operating robotic console
Dr. Jon Wee is shown here operating in the robot console, directing the robot arms.

Developments in robotic surgery are enabling procedures in minimally invasive thoracic surgery that previously were not feasible. At Brigham and Women’s Hospital, a team that includes thoracic surgeons and pulmonologists along with experts in vascular surgery, anesthesiology and intensive care has facilitated the increased use of these procedures for many different medical conditions. Read More