Brain Circuit Mapping Refines Targets for Neurostimulation

Researchers at Brigham and Women’s Hospital have developed a novel brain mapping method that suggests lesions, TMS and DBS converge on a common brain circuit for depression—which may represent a better target for therapeutic neurostimulation. The approach seems to be generalizable to other neuropsychiatric diseases.


Neural Circuit for Spirituality and Religiosity Identified

Human Brain Scan X-Rays

By using a newer technique called lesion network mapping, Michael Ferguson, PhD, Michael D. Fox, MD, PhD, of the Center for Brain Circuit Therapeutics at Brigham and Women’s Hospital, and colleagues have identified a specific brain circuit that seems to be a neural substrate for spirituality and religiosity.


COVID-19–related Psychological Factors Can Interfere with Mother–Infant Bonding

Mother holds and looks down at newborn infant

In a nationwide online survey of pregnant and postpartum women, Cindy H. Liu, PhD, and Carmina Erdei, MD, of Brigham and Women’s Hospital, and colleagues determined that psychological factors related to COVID-19, particularly grief, pose unique hazards to mother–infant bonding.


Targeting Common Causal Circuits With Brain Stimulation to Treat Depression

Can targeting certain brain circuits with therapeutic stimulation modulate neuropsychiatric symptoms? A recent study involving multiple Brigham and Women’s Hospital investigators including Michael D. Fox, MD, PhD, and Shan H. Siddiqi, MD, MBBS, answers that crucial question in the affirmative.


Studying Pandemic’s Effect on Mental Health in Young Adults

Young adults in masks at schoolThe COVID-19 pandemic has been challenging for almost everyone, and different populations have been hit in different ways. For people aged 18–30 years, it has had an outsized effect on mental health, especially in terms of depression, anxiety and post-traumatic stress disorder (PTSD).

Read More

Improving Telehealth in Psychiatry for Non-English Speakers

woman on phone at home

Telemedicine has become an increasingly important mode of care during the COVID-19 pandemic. Certain specialties lend themselves to telemedicine to a greater degree than others. One of these is psychiatry, thanks in large part to relevance of observation and conversation with patients and their families to obtain neuropsychiatric history.

Read More

Brigham Leads the Way in Brain Circuit Therapeutics

brain imaging
Dr. Siddiqi’s trial uses brain imaging to target specific circuits (white arrows). Siddiqi et al, Am J Psychiatry 2020

Brigham and Women’s Hospital recently opened its innovative Center for Brain Circuit Therapeutics. A joint clinical, research and education initiative, the new center brings together experts from neurology, psychiatry, neurosurgery and neuroradiology to develop innovative treatment methods for brain disorders that don’t respond to medication.

Read More

Brigham Researchers Awarded Two Prestigious NIH Grants

stress out woman

Researchers at Brigham and Women’s Hospital have received two grants totaling nearly $30 million from the National Institutes of Health (NIH). The grants will support two research programs — one designed to examine the effects of stress in post-menopausal women and the other to gather and analyze data that can be used to develop early-stage interventions for those at high risk for psychosis.

Read More

Care Model Has a Critical IMPACT on Patient Care in Psychiatry

person filling out clipboard

For over 20 years, the Improving Mood-Promoting Access to Collaborative Treatment (IMPACT) model has offered improved care for patients in need of psychiatric care in the primary care setting. At Brigham and Women’s Hospital, a collaborative care paradigm modeled on IMPACT is in the final stages of being rolled out to primary care practices throughout the system.

Read More

How the Brigham Meets the Psychiatric Needs of Patients in the Emergency Department

hospital bed

For many people, their first interaction with Brigham and Women’s Hospital is through the Emergency Department (ED). Usually, they are in a desperate state. As such, the ED is a critical place for patients who need acute psychiatric care.

Read More