Mass General Brigham researchers have conducted the first study to evaluate pregnancy rates in intrauterine insemination according to both total motile count (TMC) and stimulation regimen. They report encouraging data for many patients with insemination TMC <10 million.

Brigham and Women’s Hospital and Boston Children’s Hospital have performed the first-ever in-utero cerebrovascular surgery in the U.S. They successfully treated an aggressive vascular malformation in an infant’s brain before birth, preventing potentially fatal symptoms after delivery.

There are no published guidelines that address oocyte retrieval techniques for assisted reproduction. Brigham and Women’s Hospital researchers surveyed physicians about their own techniques, and although no clear top-performing technique was evident, the team suggests some principles to follow.

Andrea Lanes, MSc, PhD, of the Department of Obstetrics and Gynecology at Brigham and Women’s Hospital, and colleagues recently became the first to compare outcomes of ovarian stimulation and embryo transfer for oligoanovulatory patients with hypothalamic hypogonadism versus polycystic ovary syndrome.

Minimally invasive surgery is often promoted as a way to reduce postoperative pain after benign gynecological surgery. However, Brigham researchers found vaginal and laparoscopic hysterectomy for treatment of pelvic organ prolapse appear to be similar with regard to postoperative pain medication requirements.