Perioperative Use of Pain Medications Similar for Vaginal and Laparoscopic Repair of Pelvic Organ Prolapse

Female patient in hospital bed recovering after surgery, holding mug and looking out bright window

Minimally invasive surgery is often promoted as a way to reduce postoperative pain after benign gynecological surgery. However, Brigham researchers found vaginal and laparoscopic hysterectomy for treatment of pelvic organ prolapse appear to be similar with regard to postoperative pain medication requirements.


Sleep Discontinuity in Perimenopausal Women Linked to Female Reproductive Hormone Patterns

Woman in bed covering face, unable to sleep. Alarm clock on bed reads 3:41

The Brigham’s Jamie Coborn, PhD, Hadine Joffe, MD, and colleagues have published empirical evidence that changing hormone dynamics underlie awakenings in perimenopausal women, independent of vasomotor symptoms.


Elevated Estradiol on Day of Progesterone Initiation Is Detrimental After Frozen Embryo Transfer

Close up of green tray with researcher removing embryo frozen in liquid nitrogen for IVF procedure

Many IVF programs freeze embryos to mitigate risk of elevated estradiol levels that can negatively affect conception and live birth. However, Brigham researchers determined elevated estradiol levels at the time of progesterone initiation have similarly negative effects on outcomes after frozen embryo transfer cycles.


Blood Metabolomic Profiles May Predict Outcomes of Endometriosis Surgery in Adolescents and Young Adults

Young Black woman sitting on edge of bed holding abdomen in pain, pelvic pain endometriosis concept

About one-third of patients with endometriosis have persistent pelvic pain after surgical treatment. Brigham and Women’s Hospital researchers have conducted the first study of the relationship between presurgical blood metabolites and postsurgical pain in adolescents and young women with endometriosis.


Survey of Preeclampsia Survivors Reveals Need for Better Patient Education, Postpartum Counseling

Doctor shows information on clipboard to pregnant patient seated on table

Ellen W. Seely, MD, and colleagues used a structured survey to ascertain the experience of preeclampsia from the patient’s point of view. The responses demonstrate a need for routine, thorough patient education about preeclampsia early in pregnancy, as well as better postpartum care.


Women With IBD Are Vulnerable to Postpartum Infections

Close up of woman holding newborn infant in hospital after giving birth

Brigham and Women’s Hospital conducted the first study that examined a wide spectrum of infectious complications and included a non-IBD control group. They report a higher risk of postpartum infections in women with IBD regardless of the mode of delivery.


Ranked Best Hospital for OB/GYN in the Nation: Q&A With Nawal Nour, MD, MPH

Headshot image of Nawal Nour, MD, MPH standing in hallway smiling with arms crossed

Brigham and Women’s Hospital is ranked #1 in the nation for obstetrics and gynecology by U.S. News & World Report 2022-23. Nawal Nour, MD, MPH, chair of the Department of Obstetrics and Gynecology, discusses how the team’s dedication and perseverance has contributed to this major accomplishment.


Menopausal Hormone Therapy Linked to Increased Risk of Pituitary Adenoma

Woman sitting down holding a pack of menopausal hormone therapy pills

David J. Cote, MD, PhD, and Meir J. Stampfer, MD, DrPH, of the Channing Division of Network Medicine at Brigham and Women’s Hospital, and colleagues have conducted the first prospective study of associations between pituitary adenoma and the use of oral contraceptives or menopausal hormone therapy.


Brigham Leaders Present at PAS 2022

Over the shoulder view of woman standing at a podium with laptop, presenting to a seated audience

Leaders from the Brigham’s Department of Pediatric Newborn Medicine presented their latest research to thousands of attendees at the 2022 Pediatric Academic Societies’ meeting. The department had a strong presence at this event, which took place April 21 – 25, 2022, in Denver, CO.


Blood Test Offers Better Prediction of Preeclampsia Risk

Researcher in lab setting selecting from upright plasma samples on table

Researchers have shown that a novel molecular signature from a single blood sample can identify women at risk of preeclampsia months before presentation. They also report that molecular signatures accurately track gestational age, independently of clinical factors, and could advance the study of other complications.