A systematic review and meta-analysis by researchers at Brigham and Women’s Hospital indicates second-generation transoral incisionless fundoplication (TIF 2.0) is effective for atypical GERD (laryngopharyngeal reflux) and improves patient-centered outcomes.

The American Society of Colon and Rectal Surgeons and the Society of American Gastrointestinal and Endoscopic Surgeons published revised joint guidelines for developing enhanced recovery protocols for elective colon and rectal resection. Jennifer L. Irani, MD, at Brigham and Women’s Hospital, served as co–first author.

Clinicians in the Department of Gastroenterology, Hepatology and Endoscopy at Brigham and Women’s Hospital and colleagues explored the prevalence and perceptions of the GI hospitalist model in academic GI departments across the United States. They report GI hospitalists are relatively common and geographically diverse.

Researchers at Brigham and Women’s Hospital hypothesized that differences in mucosal gene transcript expression might explain the differences in PPI treatment response. Instead, they found the transcriptional profiles in patients with PPI-responsive and -nonresponsive eosinophilic esophagitis are remarkably similar.

Researchers in the Division of Gastroenterology, Hepatology and Endoscopy at Brigham and MIT address limitations of metals in medical devices by using liquid metal embrittlement, long viewed as a failure mechanism to be avoided, to stimulate on-demand breakdown of solid aluminum.

Researchers at Brigham and Women’s Hospital recently presented evidence of novel mechanisms by which intelectin-1 may affect an individual’s susceptibility to inflammation in the colon.