Scientific Statement: COVID-19 and Heart Failure

In September 2021, the Heart Failure Society of America published a scientific statement that discusses clinical care for patients with HF during the COVID-19 pandemic. Ankeet S. Bhatt, MD, MBA, of the Division of Cardiovascular Medicine at the Brigham, was a co-chair of the writing committee and first author.

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Knocking Out Respiratory Viruses Before They Cause Damage

Brigham researchers are seeking to limit the severe effects of respiratory viruses by using new methods to reduce the viral load and excessive lung inflammation that are common with these lung infections. Pulmonologist Bruce D. Levy, MD, is a corresponding author of a recently published article on this research.

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Study Reveals New Insights Into Source of Certain Long-Haul COVID Symptoms

doctor speaking with patient

Results of an invasive cardiopulmonary exercise test (iCPET) explain why patients with post-acute COVID-19 syndrome (PACS), also known as long-haul COVID, suffer from fatigue, shortness of breath and lightheadedness when exerting themselves. A recent study published in the journal CHEST found that PACS patients without cardiopulmonary disease demonstrate a marked reduction in aerobic activity and impaired systemic oxygen extraction, along with an exaggerated hyperventilatory response during exercise.

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Investigating Gastrointestinal Manifestations of COVID-19

COVID-19 cell

Since the beginning of the COVID-19 pandemic, Walter W. Chan, MD, MPH, director of the Center for Gastrointestinal Motility at Brigham and Women’s Hospital, and colleagues in the Division of Gastroenterology, Hepatology and Endoscopy, have led several clinical studies investigating COVID-19 infection presentation, risk factors and outcomes on the gastrointestinal (GI) system.

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Uncovering Risks for Severe AKI in COVID-19 Patients

Dialysis machine

Infection with SARS-CoV-2 can affect any organ system in the body, and acute kidney injury (AKI) is common in people with more severe cases of COVID-19. Researchers at Brigham and Women’s Hospital recently led a study that looked at critically ill patients with COVID-19 and identified both patient- and hospital-level risk factors for development of AKI treated with dialysis.

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Major Adverse Cardiovascular Events Associated With COVID-19

patient in hospital bed

Several cardiovascular complications have been associated with COVID-19, according to a recent multicenter, observational cohort study conducted by researchers at Brigham and Women’s Hospital and published in the Journal of the American College of Cardiology.

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The Brigham Expands Use of ECMO During COVID-19

extracorporeal membrane oxygenation (ECMO) machine

In March of 2020, Brigham and Women’s Hospital purchased four additional extracorporeal membrane oxygenation (ECMO) machines to prepare for a possible surge of COVID-19. It wasn’t yet clear if ECMO could support critically ill COVID-19 patients, but early reports from China had shown promise.

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Brigham Takes on Leadership Role in COVID-19 Vaccine Trials

Person gettting vaccine in arm

A late-stage clinical trial is now underway at Brigham and Women’s Hospital to test a vaccine candidate for preventing COVID-19. The Brigham is the only hospital in New England to serve as a clinical research site in the phase 3 COVE study. The study is designed to evaluate the effectiveness and safety of the vaccine, mRNA-1273, and its ability to prevent COVID-19 illness.

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Treating Critically Ill Pregnant Patients with COVID-19

pregnant woman in hospital bed

At Brigham and Women’s Hospital, the Department of Obstetrics and Gynecology and Division of Maternal-Fetal Medicine have a long history of caring for patients with complex health conditions that affect pregnant women, including placenta accreta and heart disease.

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Outpatient Prenatal Care During COVID-19

pregnant woman sitting on couch

The COVID-19 pandemic has uniquely affected outpatient prenatal care, which depends on frequent assessment of a pregnant mother and her fetus. At the start of the pandemic, the outpatient prenatal care program at Brigham and Women’s Hospital increased the use of virtual visits, allowing patients to regularly meet with their providers safely.

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