Latest Clinical & Research News
COVID-19 News
Emily Moldoff, NP, Carleton Eduardo Corrales, MD, and Jennifer J. Shin, MD, and colleagues have documented that the noise generated by powered air-purifying respirators creates a substantial barrier to communication during clinical interactions.
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In a nationwide online survey of pregnant and postpartum women, Cindy H. Liu, PhD, and Carmina Erdei, MD, of Brigham and Women’s Hospital, and colleagues determined that psychological factors related to COVID-19, particularly grief, pose unique hazards to mother–infant bonding.
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In September 2021, the Heart Failure Society of America published a scientific statement that discusses clinical care for patients with HF during the COVID-19 pandemic. Ankeet S. Bhatt, MD, MBA, of the Division of Cardiovascular Medicine at the Brigham, was a co-chair of the writing committee and first author.
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Brigham researchers are seeking to limit the severe effects of respiratory viruses by using new methods to reduce the viral load and excessive lung inflammation that are common with these lung infections. Pulmonologist Bruce D. Levy, MD, is a corresponding author of a recently published article on this research.
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Results of an invasive cardiopulmonary exercise test (iCPET) explain why patients with post-acute COVID-19 syndrome (PACS), also known as long-haul COVID, suffer from fatigue, shortness of breath and lightheadedness when exerting themselves. A recent study published in the journal CHEST found that PACS patients without cardiopulmonary disease demonstrate a marked reduction in aerobic activity and impaired systemic oxygen extraction, along with an exaggerated hyperventilatory response during exercise.
Since the beginning of the COVID-19 pandemic, Walter W. Chan, MD, MPH, director of the Center for Gastrointestinal Motility at Brigham and Women’s Hospital, and colleagues in the Division of Gastroenterology, Hepatology and Endoscopy, have led several clinical studies investigating COVID-19 infection presentation, risk factors and outcomes on the gastrointestinal (GI) system.
Infection with SARS-CoV-2 can affect any organ system in the body, and acute kidney injury (AKI) is common in people with more severe cases of COVID-19. Researchers at Brigham and Women’s Hospital recently led a study that looked at critically ill patients with COVID-19 and identified both patient- and hospital-level risk factors for development of AKI treated with dialysis.
Several cardiovascular complications have been associated with COVID-19, according to a recent multicenter, observational cohort study conducted by researchers at Brigham and Women’s Hospital and published in the Journal of the American College of Cardiology.
In March of 2020, Brigham and Women’s Hospital purchased four additional extracorporeal membrane oxygenation (ECMO) machines to prepare for a possible surge of COVID-19. It wasn’t yet clear if ECMO could support critically ill COVID-19 patients, but early reports from China had shown promise.
A late-stage clinical trial is now underway at Brigham and Women’s Hospital to test a vaccine candidate for preventing COVID-19. The Brigham is the only hospital in New England to serve as a clinical research site in the phase 3 COVE study. The study is designed to evaluate the effectiveness and safety of the vaccine, mRNA-1273, and its ability to prevent COVID-19 illness.