Adults With TBI May Benefit From Screening for Cardiometabolic Disease, Other Comorbidities

Female doctor shows brain scan images to older male patient in hospital bed

An analysis of prospectively collected data has demonstrated that adults who sustain traumatic brain injury (TBI), regardless of age and injury severity, are at higher risk of certain cardiovascular, endocrine, neurologic, and psychiatric disorders.


Disparities Noted in Uptake of Cholecystectomy for Idiopathic Pancreatitis

Surgeon performs laparoscopic cholecystectomy on patient

Idiopathic acute pancreatitis (IAP) is an emerging indication for empiric inpatient cholecystectomy. Researchers at Brigham and Women’s Hospital recently found an extremely low rate of adoption and also report disparities in uptake by demographics and geography.


Rates of Spinal Symptoms and Spinal Surgery Are Lower After Bariatric Surgery

Doctor holds up x-ray of spine to show older patient

A study showed patients with a history of bariatric surgery had lower overall complication rates after spinal surgery than morbidly obese patients who did not have bariatric surgery. Now researchers report significant reductions in symptomatic spinal disorders and the need for spinal surgery after bariatric surgery.


Review: Targeting Oncometabolism to Maximize Immunotherapy in Brain Cancer

Cells stained with different colors in a false color image of a tumour sample

Joshua D. Bernstock, MD, PhD, in the Department of Neurosurgery at Brigham and Women’s Hospital, Gregory K. Friedman, MD, of the University of Alabama at Birmingham, and colleagues reviewed novel therapies that target oncometabolism and tumor immunometabolism.


Ranked Best Hospital for OB/GYN in the Nation: Q&A With Nawal Nour, MD, MPH

Headshot image of Nawal Nour, MD, MPH standing in hallway smiling with arms crossed

Brigham and Women’s Hospital is ranked #1 in the nation for obstetrics and gynecology by U.S. News & World Report 2022-23. Nawal Nour, MD, MPH, chair of the Department of Obstetrics and Gynecology, discusses how the team’s dedication and perseverance has contributed to this major accomplishment.


Editorial: Meaningless Applications and Misguided Methodologies of AI-Related Research in Orthopedics

Researcher working on multiple displays showing artifical intelligence, machine learning concept

Prem N. Ramkumar, MD, MBA, of the Orthopaedic Machine Learning Laboratory at Brigham and Women’s Hospital, and colleagues want orthopedic surgeons to understand artificial intelligence (AI) better but critically assess AI-related reporting in the medical literature.


Brigham Offering Magnetic Sphincter Augmentation for Patients With GERD

LINX product shown banded around a diagram of the lower esophageal sphincter above stomach

Magnetic sphincter augmentation using the LINX® Reflux Management System is an alternative to acid suppression therapy with proton pump inhibitors or traditional surgical treatment. Gastrointestinal and bariatric surgeons Thomas C. Tsai, MD, MPH, and David Spector, MD, discuss bringing this procedure to the Brigham.


Novel AI Model Helps Detect Cardiac Allograft Rejection From Endomyocardial Biopsies

Hematoxylin and eosin–stained biopsy of muscle fibers of heart myocardium

Researchers at Brigham and Women’s Hospital have created Cardiac Rejection Assessment Neural Estimator (CRANE), a form of artificial intelligence for automated screening of endomyocardial biopsy results. They describe its performance and its potential to serve as an assistive diagnostic tool.


Cocoa Extract Supplementation Shows Promise in Reducing Cardiovascular Events

Top view close up of many cocoa seeds

Researchers conducted the first rigorous, large-scale trial of long-term cocoa flavanol supplementation to prevent CVD and cancer. They found that cocoa extract supplementation led to a small but nonsignificant reduction in total cardiovascular events among older adults but significantly reduced CVD death by 27%.


The Brigham Presents Four Late-breaking Clinical Trials at ACC 2022

Three headshots of Drs. Brian Bergmark, Deepak Bhatt, and Paul Ridker

Three cardiologists from the Division of Cardiovascular Medicine at the Brigham’s Heart & Vascular Center—Brian A. Bergmark, MD, Deepak L. Bhatt, MD, MPH, and Paul M. Ridker, MD, MPH—presented a total of four late-breaking clinical trials at the American College of Cardiology’s 71st Annual Scientific Session in April.