Latest Clinical & Research News
An increasing percentage of patients seeking in vitro fertilization (IVF) are obese, and many experience disappointing outcomes. Brigham researchers recently examined the impact of increasing BMI on IVF, obstetric, and perinatal outcomes, and they report largely similar outcomes across BMIs of 30 to 60.
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Direct oral anticoagulants (DOACs) are preferred to vitamin K antagonists for stroke prevention in atrial fibrillation, acute treatment and extended-duration secondary prevention of venous thromboembolism in most patients. However, DOACs may be less efficacious or safe compared to standard of care in other conditions.
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Brigham and Women’s Hospital researchers present evidence that pharmacologic treatment of depression/anxiety is associated with improved mental well-being in patients with hip or knee osteoarthritis but doesn’t seem to improve physical function or pain levels.
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Gary W. Liu, PhD, Giovanni Traverso, MD, PhD, MBBCH, of the Division of Gastroenterology, Hepatology and Endoscopy at Brigham and Women’s Hospital, and colleagues show how a drinkable formulation called LIFT hydrogels could expand access to advanced therapeutics for people who have trouble swallowing pills.
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Brigham and Women’s Hospital researchers have demonstrated that a point-of-care ultrasound (POCUS)-first approach for evaluating nephrolithiasis in patients who meet certain criteria could produce substantial national cost savings, as well as clinical benefits.
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A recent scientific statement by The Lupus Foundation of America’s Health Disparities Advisory Panel, which includes Karen Costenbader, MD, MPH, addresses the relationship between social determinants of health and racial and ethnic disparities in lupus. It also recommends potential interventions to reduce disparities.
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Brigham and Women’s Hospital researchers have confirmed in a large cohort what previous research suggested: a lack of correlation between subjective dysautonomia and standardized objective testing.
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Using deep brain stimulation (DBS) as a research tool, Brigham and Women’s Hospital scientists have identified distinct neural circuits for Parkinson’s disease, dystonia, obsessive-compulsive disorder (OCD), and Tourette’s syndrome.
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Behnood Bikdeli, MD, MS, at Brigham and Women’s Hospital, David Jiménez, MD, PhD, at Hospital Ramón y Cajal in Madrid, and colleagues recently conducted the first study to compare the prognostic relevance of cTnI with hs-cTnI in patients with pulmonary embolism (PE).
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A multi-institutional research group co-led by D. Branch Moody, MD, of Brigham and Women’s Hospital, received an Ammodo Science Award for their groundbreaking research on lipid molecules. Their goal is to develop effective diagnostic tests and vaccines against tuberculosis and other infectious diseases.
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