Exploring Cognitive Impairment in Hematologic Cancer Patients

Many older patients with hematologic cancers have another condition to worry about—one they don’t always feel comfortable discussing with their health care team. As people are living longer, memory problems have become increasingly prevalent. However, little is known about the impact of cognitive impairment, and specific domains of cognitive impairment, on older cancer patients and their survival.

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Nasal Vaccine for Alzheimer’s Disease Nears Human Trials

Reduction in Aβ-levels (green) in mice after weekly intranasal Protollin for 6 weeks in treated (right) versus control (left)*

An intranasal vaccine for Alzheimer’s disease (AD) is expected to begin its first human trial in 2020, culminating nearly 25 years of research led by Howard L. Weiner, MD, co-director of the Ann Romney Center for Neurologic Diseases at Brigham and Women’s Hospital.

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WATCH-DM Risk Score Predicts Heart Failure Risk in Diabetes Patients

Senior woman with glucometer checking blood sugar level at home. Diabetes, health care conceptIn September 2019, results from the DAPA-HF trial revealed that SGLT2 inhibitors may be helpful for patients with heart failure. These therapies may also be used to prevent heart failure in patients with diabetes*. However, a way of accurately identifying which diabetes patients are most at risk for heart failure has been elusive.
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The Genie Study Explores Effects of Diet on Steroid-Resistant FSGS

a medical professional takes a young man's blood pressureIt can be challenging to assess the effects of dietary changes on a disease, especially when those changes involve eliminating common, often beloved foods from a child’s diet. However, Leonardo D. Riella, MD, PhD, FASN, associate director of kidney transplantation at Brigham and Women’s Hospital, found a way to make the elimination process both effective from a research perspective and fun for a group of young kidney disease patients.
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New Option for Severe Emphysema: One-Way Valves to Reduce Lung Volume

Adding to the care options for patients with advanced emphysema, the Lung Center at Brigham and Women’s Hospital now offers a new procedure to place one-way endobronchial valves into the airways of a diseased lobe. The valves offer the symptom relief of lung reduction without the risks of surgery.
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Discovering the Genetic Blueprint Behind Chronic Obstructive Pulmonary Disease

Edwin Silverman, MD, PhD, is a pioneer in studying how genetics impact COPD risk. His team, which includes leading researchers such as Craig Hersh, MD, MPH; Dawn DeMeo, MD, MPH; Michael Cho, MD, MPH; Peter Castaldi, MD; and Xiaobo Zhou, PhD, generated findings that could have profound implications for the future of COPD treatment.

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Improving Perioperative Care in Foot and Ankle Surgery

Doctor giving a patient foot treatment

For over a decade, the Foot and Ankle Service in the Department of Orthopaedic Surgery at Brigham and Women’s Hospital has conducted research that places a strong emphasis on optimizing perioperative care for foot and ankle surgery patients.

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Inventing a “Better Way”: Developing Devices to Improve Minimally Invasive Gynecologic Surgery

Jon I. Einarsson, MD, MPH
Jon I. Einarsson, MD, MPH, didn’t set out to be an inventor. Chief of the Division of Minimally Invasive Gynecologic Surgery at Brigham and Women’s Hospital, Einarsson is a champion of minimally invasive approaches for their benefits to patients. But as a teacher and mentor, he knows that some techniques that benefit patients are slightly more challenging technically for trainees and others to master.
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Restoration of Infertility Using Patient-Specific Stem Cells

For women who want their own biological children, a diagnosis of infertility due to a lack of viable eggs can be devastating. Ovarian failure in women can have many causes, including aging, autoimmune disease and exposure to radiation therapy and certain chemotherapy drugs.
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Reducing Long-Term CV Risks after Preeclampsia through Online Intervention and Communication

An online intervention program for women who recently had preeclampsia has produced insight into how to reduce their future risks of cardiovascular disease.

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