Feasibility Study: Multi-Section Robotic Ureteroscope Outperforms Flexible Scope

Anatomy structure of human kidneys

Researchers at Brigham and Women’s Hospital modified a robotic-assisted cardiac catheter ablation device to treat kidney stones and compared it with a standard flexible ureteroscope. They found the robotic device was more maneuverable and facilitated precision aim at targets in each renal calyx.


BPH Histopathologic Subtypes Do Not Influence Outcomes of TURP

Illustration showing healthy prostate and benign prostatic hyperplasia

In the first study of its kind, Brigham and Women’s Hospital researchers investigated whether the stromal‐predominant benign prostatic hyperplasia (BPH) subtype negatively affects outcomes of transurethral resection of the prostate, as reactive stromal myofibroblasts support a progressive inflammatory response.


Delay in Salvage Therapy Increases Risk of Death for Some Prostate Cancer Patients

Study led by Anthony Victor D'Amico, MD, PhD, chief of Genitourinary Radiation Oncology, Dana-Farber Brigham Cancer Center.

A recently approved and widely adopted imaging study that improves detection of prostate cancer recurrence in patients who have undergone radical prostatectomy is having an unintended effect of delaying potentially life-saving salvage treatment with radiation and androgen deprivation therapy, according to a study led by Anthony Victor D’Amico, MD, PhD, chief of Genitourinary Radiation Oncology, Dana-Farber Brigham Cancer Center.

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Benefits of Electronic Health Records in the Management of Hypogonadal Men

Doctor working on laptop computer and medical stethoscope on clipboard on desk, EHR concept

Electronic health records (EHRs) have multiple benefits for both clinicians and patients, but can lead to clinician burnout. Martin Kathrins, MD, and Anna Goldman, MD, of Brigham and Women’s Hospital, discuss how EHRs can optimize the treatment of hypogonadal men.


5-item Frailty Index Predicts Complications of Endoscopic Treatment for Benign Prostatic Obstruction

Urologist pointing to anatomical model of male reproductive system

The 5-item Frailty Index (5i-FI) accurately predicts morbidity and mortality after radical prostatectomy, cystectomy, and partial nephrectomy. Now, Brigham researchers report the 5i-FI is also useful for predicting surgical complications after endoscopic treatment for benign prostatic obstruction.


Pilot Study: Analyzing Urologists’ Efficiency During Ureteroscopy

Closeup Image of Flexible Ureteroscope Device in Container

Flexible ureteroscopy (URS) is the most commonly used surgical procedure to treat nephrolithiasis, and Brigham researchers have begun to evaluate how surgeon movements affect URS efficiency. They report results from a pilot study that should inform improvement in endoscopist training and evaluation.


Reducing Healthcare Disparities: Q&A With Quoc-Dien Trinh, MD, MBA

Female doctor showing tablet to black male patient in hospital bed

As part of the United Against Racism initiative, Mass General Brigham implemented outreach programs across the system to reduce healthcare disparities. Quoc-Dien Trinh, MD, MBA, discusses the program he co-founded and the research his team is doing to improve care for people of color at Brigham and Women’s Hospital.


Biodegradable Implantable Device Developed for Intravesical Therapy of Bladder Disorders

3D rendering of human bladder anatomy highlighted orange

Implantable devices for drug delivery to the bladder require surgical implantation and removal. Scientists at Brigham and Women’s Hospital have invented a biodegradable ring-shaped implantable device (BRID) for long-term and local drug delivery inside the bladder that does not require a retrieval procedure.


Brigham Researchers Develop Efficient Method to Generate Ureteric Bud, First Human Functional Collecting Duct Principal and Intercalated Cells

Doctor holds anatomical model of a human kidney, pointing to it while seated at desk

Creating kidney organoids for preclinical research poses a challenge due to their complex architecture. Brigham researchers have developed an efficient method for generating functional ureteric bud and collecting ducts organoids, which drive the growth and radial organization of the developing kidney.


Predictors of Healthcare Spending Identified in Patients With Gout Using Urate-lowering Therapy

Female patient in office signing paperwork across from doctor

Researchers at Brigham and Women’s Hospital identified three distinct groups of gout patients according to their patterns of total spending on health care. The team provides information on identifying patients with gout who could benefit from interventions to reduce long-term spending.