On May 16 – 19, 2024, faculty from the Heart & Vascular Center at Brigham and Women’s Hospital will join the international electrophysiology community and present their latest research at the Heart Rhythm 2024 annual meeting.

Researchers from the Brigham, the Broad Institute, and Stanford Medicine combined multiple sequencing and experimental techniques to map the relationship between known coronary artery disease (CAD) variants and the biological pathways they impact.

Brigham researchers have developed a method for identifying hidden genetic contributors to disease by applying various stress tests to human blood cells. The evoked cellular response traits they observed pinpointed genes and pathways relevant to multiple cardiometabolic and inflammatory diseases.

Brigham and Women’s Hospital cardiovascular experts will present their latest research at this year’s American College of Cardiology 2024 Scientific Session & Expo, held April 6–8 in Atlanta, GA.

Paul M. Ridker, MD, MPH, of the Center for Cardiovascular Disease Prevention at Brigham and Women’s Hospital, and colleagues found inflammation assessed by hsCRP predicted cardiovascular events and death at least as strongly as LDLC when comparing bempedoic acid with placebo in statin-intolerant patients.

Shinichi Goto, PhD, at Brigham and Women’s Hospital, and colleagues have developed a deep learning–based model that detects subtle changes in standard 12-lead electrocardiography data to flag patients who should undergo echocardiography to evaluate possible atrial septal defect.

The fact that cardiovascular disease is the leading cause of death in women is wildly underappreciated, says the Brigham’s JoAnn E. Manson, MD, MPH, DrPH. Dr. Manson has led many seminal research projects focused on women’s health and set the foundation for related advances at the Brigham today.