GLP-1RA Use Linked to Reduced COPD Exacerbation Rates Compared With Other Diabetes Therapies

Brigham and Women’s Hospital researchers report that patients with type 2 diabetes and chronic obstructive pulmonary disease (COPD) who initiate GLP-1RA have a decreased risk of both moderate and severe COPD exacerbations compared to users of sulfonylureas or dipeptidyl peptidase 4 inhibitors.

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Extracorporeal Cardiopulmonary Resuscitation Protocol on Preventing Sudden Cardiac Arrest Deaths

Conventional CPR, which combines rescue breathing with chest compressions, has been the primary treatment for cardiac arrest for nearly 60 years. Survival, however, remains frustratingly low. Brigham and Women’s Hospital is part of a collaborative effort to explore a promising new alternative: extracorporeal…

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Brigham OB/GYN Ranks #1 in the Nation for Third Consecutive Year

Department Chair Nawal Nour, MD, MPH, MBA, reflects on U.S. News & World Report 2024-25 ranking Brigham and Women’s Hospital #1 in the nation for Obstetrics and Gynecology. She celebrates how the Department’s commitment to collaboration and transparency helps provide high quality, equitable OB/GYN care to patients.

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Adding EHR Notes to Claims Data Improves Accuracy of Automated Gout Flare Ascertainment

Studying the comparative effectiveness of gout treatments is hindered by the difficulty of identifying instances of gout flare. Brigham and Women’s Hospital researchers have determined that combining claims data with information from narrative notes in the electronic health record improves the capture of gout flares.

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IVF Need Not Be Withheld From Patients With Obesity

An increasing percentage of patients seeking in vitro fertilization (IVF) are obese, and many experience disappointing outcomes. Brigham researchers recently examined the impact of increasing BMI on IVF, obstetric, and perinatal outcomes, and they report largely similar outcomes across BMIs of 30 to 60.

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Review: When Direct Oral Anticoagulants Should Not Be Standard Treatment

Direct oral anticoagulants (DOACs) are preferred to vitamin K antagonists for stroke prevention in atrial fibrillation, acute treatment and extended-duration secondary prevention of venous thromboembolism in most patients. However, DOACs may be less efficacious or safe compared to standard of care in other conditions.

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Treatment of Depression/Anxiety in Osteoarthritis Linked to Better Psychological Health But Not Improved Physical Symptoms

Brigham and Women’s Hospital researchers present evidence that pharmacologic treatment of depression/anxiety is associated with improved mental well-being in patients with hip or knee osteoarthritis but doesn’t seem to improve physical function or pain levels.

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Drinkable Hydrogels Bridge the Gap Between Pills and Liquid Therapies

Gary W. Liu, PhD, Giovanni Traverso, MD, PhD, MBBCH, of the Division of Gastroenterology, Hepatology and Endoscopy at Brigham and Women’s Hospital, and colleagues show how a drinkable formulation called LIFT hydrogels could expand access to advanced therapeutics for people who have trouble swallowing pills.

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Ultrasound-First Nephrolithiasis Evaluation for Appropriate Patients Would Reduce U.S. Costs by Millions

Brigham and Women’s Hospital researchers have demonstrated that a point-of-care ultrasound (POCUS)-first approach for evaluating nephrolithiasis in patients who meet certain criteria could produce substantial national cost savings, as well as clinical benefits.

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Scientific Statement: Disparities in Lupus Outcomes and the Role of Social Determinants of Health

A recent scientific statement by The Lupus Foundation of America’s Health Disparities Advisory Panel, which includes Karen Costenbader, MD, MPH, addresses the relationship between social determinants of health and racial and ethnic disparities in lupus. It also recommends potential interventions to reduce disparities.

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