Stark Differences Found in Hospital-level Patterns of Nonoperative Management for Low-risk Thyroid and Kidney Cancers

A growing set of low-risk cancers, including early-stage thyroid and kidney cancers, is associated with excellent outcomes regardless of management strategy. Given the risks associated with overtreatment of these cancers, it follows that many patients should be treated nonoperatively. Read More

Manipulation May Be Preferable to Arthroscopy for Treating Arthrofibrosis After TKA

Nathan P. Thomas, MD, PhD, Antonia F. Chen, MD, MBA, in the Department of Orthopaedic Surgery at Brigham and Women’s Hospital, and colleagues compared manipulation under anesthesia or arthroscopic lysis of adhesions in the largest cohort in current literature.


Follow-up of Orthopedic Trauma Patients Declines Once Global Period Ends

Closeup midsection of a man with broken arm in cast, orthopedic trauma recovery

Researchers at Brigham and Women’s Hospital recently demonstrated that the post-surgical global period is a critical timepoint influencing follow-up rates. At six months, follow-up was lowest for patients on Medicaid.


Developing the First SLE Risk Prediction Model Based on Known Factors

Woman sitting on couch touching left shoulder in discomfort, joint pain from lupus SLE concept

Brigham rheumatologist and Lupus Program director Karen Costenbader, MD, MPH, helped develop a risk prediction model for systemic lupus erythematosus (SLE) incorporating genetic, environmental, and lifestyle risk factors, as well as family history. Clinicians one day may use the model to predict individuals’ SLE risks.


SSO 2023 International Conference on Surgical Cancer Care Presenters

The Society of Surgical Oncology (SSO) is holding its annual International Conference on Surgical Cancer Care in Boston on March 22-25.

Several leaders in surgical oncology from Brigham and Women’s Hospital/Dana-Farber Brigham Cancer Center will present their latest research and clinical advancements in breast cancer, colorectal cancer, melanoma, sarcoma, and more. Read More

3D Bioprinting Yields Blood Vessels Mechanically, Functionally Comparable to Native Vessels

Research 3D bioprinter for 3D printing cells onto an petri dish

Researchers at Brigham and Women’s Hospital have developed a stretchable double-network hydrogel bioink system for microfluidic bioprinting of small-diameter vascular conduits. They say the conduits recapitulate the structural and biological functions of native blood vessels.


Novel Localization of MS-related Depression May Allow Therapeutic Brain Stimulation

Researchers at Brigham and Women’s Hospital recently demonstrated that lesions causing depression in patients with stroke or penetrating head trauma were functionally connected to a common brain circuit.


Review: Precision Medicine for Multiple Sclerosis

Key decision points in multiple sclerosis (MS) management would benefit from precision medicine—using information about an individual’s genomics, environment, and lifestyle, not just their signs and symptoms—to subtype their disease and make personalized decisions about their treatment.


Women Substantially More Likely Than Men to Decline Statin Therapy

Female doctor shows elderly female patient something on paper in doctor's office, diagnosis concept

In the first large, population-based cohort study of the issue, researchers at Brigham and Women’s Hospital found 22% of eligible patients declined statin therapy initially and 6% never accepted the recommendation. Results on both measures were significantly higher for women than men.