Latest Clinical & Research News
Brigham AI researcher and radiation oncologist Danielle S. Bitterman, MD, is part of the team behind TRIPOD-LLM, a tool that standardizes reporting guidelines for authors of studies focused on biomedical and healthcare large language models.
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The Brigham’s Francisco J. Quintana, PhD, explores the stability of disease-associated astrocytes, their regulation, and whether they integrate past stimulation events to respond to subsequent challenges. This work could lead to new therapeutic approaches for multiple sclerosis and other neurological diseases.
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Data show that C-reactive protein, LDL cholesterol, and lipoprotein(a) effectively predict heart disease in women.
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A multicenter team led by the Brigham used patient data compiled from three large clinical trials to identify potential prognostic biomarkers that could be used to risk-stratify patients with atrial fibrillation based on their heart failure risk. First author Paul Haller, MD, PhD, discusses the study’s implications.
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Research has found that people taking GLP-1 weight-loss drugs had significantly lower risk of death from COVID-19 and other infectious and cardiovascular causes.
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About one-third of epilepsy patients have a disease that is considered drug-resistant, meaning they have failed at least two medications. For these individuals, neurosurgical procedures offer the best chance of bringing their disease under control. Remarkably, the average time it takes for someone with…
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Although current surgical approaches for treating drug-resistant epilepsy are already good, researchers at the Brigham are focused on developing treatments that are even more effective and less invasive. John David Rolston, MD, PhD, director of Epilepsy Surgery, highlights some of these promising efforts.
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The V142I variant of the TTR gene, common among Black Americans, increases risks of cardiac amyloidosis, heart failure, and early mortality.
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A Brigham and Women’s Hospital research team established baseline epidemiological information about a new paradigm called cardiovascular, kidney, and metabolic (CKM) syndrome.
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Researchers at Brigham and Women’s Hospital developed a novel aortic stenosis polygenic risk score (PRS) that incorporates more than five million genetic variants. They verified it was associated with aortic stenosis in two independent, very large populations.
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