Research Reveals New Biomarkers for Heart Disease
Data show that C-reactive protein, LDL cholesterol, and lipoprotein(a) effectively predict heart disease in women.
Read More... Biomarkers May Help Predict Risk of Heart Failure in Patients With Atrial Fibrillation
A multicenter team led by the Brigham used patient data compiled from three large clinical trials to identify potential prognostic biomarkers that could be used to risk-stratify patients with atrial fibrillation based on their heart failure risk. First author Paul Haller, MD, PhD, discusses the study’s implications.
Read More...Semaglutide Lowers Risk of COVID Death
Research has found that people taking GLP-1 weight-loss drugs had significantly lower risk of death from COVID-19 and other infectious and cardiovascular causes.
Read More...Crossing Barriers in CNS Repair: Dr. Fengfeng Bei on Neural Regeneration and Gene Therapy
About one-third of epilepsy patients have a disease that is considered drug-resistant, meaning they have failed at least two medications. For these individuals, neurosurgical procedures offer the best chance of bringing their disease under control. Remarkably, the average time it takes for someone with…
Read More...Improving Outcomes for Patients With Drug-resistant Epilepsy Through Surgery
Although current surgical approaches for treating drug-resistant epilepsy are already good, researchers at the Brigham are focused on developing treatments that are even more effective and less invasive. John David Rolston, MD, PhD, director of Epilepsy Surgery, highlights some of these promising efforts.
Read More...Genetic Mutation in Black Americans Boosts Risk of Transthyretin Amyloidosis
The V142I variant of the TTR gene, common among Black Americans, increases risks of cardiac amyloidosis, heart failure, and early mortality.
Read More...Study Finds 90% of Adults Have Stage 1 or Higher CKM Syndrome
A Brigham and Women’s Hospital research team established baseline epidemiological information about a new paradigm called cardiovascular, kidney, and metabolic (CKM) syndrome.
Read More...Novel Polygenic Risk Score Validated for Aortic Stenosis
Researchers at Brigham and Women’s Hospital developed a novel aortic stenosis polygenic risk score (PRS) that incorporates more than five million genetic variants. They verified it was associated with aortic stenosis in two independent, very large populations.
Read More...Mock Code Program Goes Beyond CPR to Test Brigham’s Emergency Response Systems
The Brigham and Women’s Hospital mock code program plans and conducts high-fidelity in situ simulations that not only allow participants to practice critical resuscitations but also test hospital systems for emergency response. Paul Jansson, MD, MS, and Andrew Eyre, MD, MS, elaborate on what distinguishes the program.
Read More...Nasal Tuft Cells Direct the Olfactory Mucosal Response to Allergens
Researchers at Brigham and Women’s Hospital report that TRPM5+ MVCs in the olfactory neuroepithelium not only are tuft cells but also have a role beyond triggering inflammation: they regulate olfactory stem cell proliferation.
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