Latest Clinical & Research News
Specialty: Geriatric
The Brigham’s Vadim N. Gladyshev, PhD, and colleagues have developed an epigenetic clock that allows predictions of biological age at the single-cell level, pointing to a new direction of aging research with applications for somatic, germline and cancer cells.
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Ariela Orkaby MD, MPH, of the Brigham’s Division of Aging, and colleagues report that increased frailty status as rated on the Clinical Frailty Scale is associated with increased mortality in older adults after in-hospital cardiopulmonary resuscitation.
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Lisa Cooper, MD, and Houman Javedan, MD, of the Division of Aging at the Brigham, and colleagues have adapted the comprehensive geriatric assessment (FI-CGA) tool to be feasible for use by geriatricians to communicate complex geriatric concepts with multiple other clinics at the Brigham that care for older adults.
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A retrospective study at the Brigham, led by Lisa Cooper, MD, and Laura N. Frain, MD, MPH, found that polypharmacy, potentially inappropriate medications, and frailty were not associated with complications after surgery for thoracic malignancies, but frailty was associated with increased length of hospital stay.
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The COVID-19 pandemic had prompted a 130-fold increase in telehealth visits by U.S. Medicare recipients. The Division of Aging at the Brigham was part of that surge, adapting the comprehensive geriatric assessment (CGA) to be suitable for telephone and video visits.
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While clinicians have several tools at their disposal to determine whether patients are delirious, researchers at the Brigham are going a step further by focusing on the severity of delirium. Geriatrician Tammy T. Hshieh, MD, MPH, discusses a more nuanced delirium rating tool featured in a recently published study.
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The COVID-19 pandemic has sparked a rapid shift to telemedicine across health care. Among the many challenges this new reality has created for geriatricians is how to adapt the comprehensive geriatric assessment (CGA) to a virtual delivery format.
It is well-established that chronic inflammation may lead to frailty. Less understood is the potential of anti-inflammatory medications such as aspirin to prevent this state of increased vulnerability.
The Centers for Disease Control and Prevention (CDC) reports that 8 out of 10 COVID-19-related deaths in the United States have been in adults 65 years and older. As such, the novel coronavirus pandemic has had a dramatic impact on geriatric care.
U.S. veterans aged 75 years or older who were prescribed statins had a 25 percent lower risk of death than their counterparts, according to a retrospective cohort study led by investigators from Brigham and Women’s Hospital and the VA Boston Healthcare System. The analysis also found the risk of dying from a cardiovascular event, such as a heart attack or stroke, was lower by 20 percent among veterans treated with statins.