Many Patients With Comorbid Depression or Anxiety Need Less Psychological Treatment After Rotator Cuff Repair

Cale Jacobs, PhD, of the Department of Orthopaedic Surgery at Brigham and Women’s Hospital, and colleagues have measured the utilization of treatment for depression and anxiety after arthroscopic rotator cuff repair.


Celebrating the 100th Anniversary of Breakthrough in Management of Mitral Valve Disease

Claude Beck, Eliot Cutler, Samuel Levine sitting at desk looking at papers, doctors working as team

In 1923, Dr. Elliot C. Cutler conducted the world’s first successful mitral valvuloplasty at the Brigham (then Peter Bent Brigham Hospital). On October 20, 2023, the Brigham will mark this important milestone with an all-day CME event looking at past, present, and future approaches to managing mitral valve disease.


TNF Inhibitors Not Very Effective Against Axial Spondyloarthritis in Patients With IBD

Axial spondyloarthritis (axSpA) is a common extraintestinal manifestation of inflammatory bowel disease (IBD). Anti-TNF agents are often used to treat concomitant axSpA and IBD. Brigham researchers have presented evidence that TNF inhibitors are less effective for axSpA than for IBD within one year.


Treatment Benefits and Safety of Sacubitril/Valsartan Are Maintained Despite Early eGFR Decline

Brigham and Women’s Hospital researchers found moderate eGFR decline when transitioning from a renin–angiotensin system inhibitor (RASi) to SV was not consistently associated with adverse outcomes. In addition, long-term benefits of SV were retained in patients with HF across a broad range of initial eGFR declines.


Review: An Ecological Framework for Racial and Ethnic Disparities in Surgery

Racial/ethnic minority groups in the U.S. have higher mortality rates after surgical procedures than white individuals. Brigham and Women’s Hospital researchers have developed an analytic model of four interconnected sets of macro-level factors that influence access to high-quality, evidence-based surgical care.


Brigham Researchers Map More Than 2,000 CD1-binding Lipids for T Cells

Lipid T Cell Blocker

Brigham scientists developed a method to simultaneously detect more than 2,000 CD1 lipid molecules that are displayed to T cells in the human immune system. This resulted in the first integrated CD1 lipidomic map, guiding the investigation of lipid T cell antigens and cleft blockers in any cellular system or disease.


Stopping Opioids After Surgery (SOS) Score Validated for Broad Range of Patients Undergoing Orthopedic Surgery

Andrew J. Schoenfeld, MD, MSc, of the Department of Orthopaedic Surgery at the Brigham, and colleagues have now validated the Stopping Opioids after Surgery (SOS) score for use after a diverse array of orthopedic procedures across subspecialties.


Study Reveals Pathogenic Role of Eosinophils in Atherosclerosis

3d rendered medically accurate illustration of an eosinophil

A recent study co-led by Guo-Ping Shi, ScD, and Zhaojie Meng, PhD, of the Division of Cardiovascular Medicine at Brigham and Women’s Hospital, is the first to identify a receptor for eosinophil cationic protein and define its pathogenic role in atherosclerosis.


Brigham Urology Hosts International Advances in Urologic Care Symposium

Image of coastline in the Dominican Republic

This fall, Brigham and Women’s Hospital faculty host an international scientific conference on urology in the Dominican Republic. Course directors Matthew Mossanen, MD, MPH, and Quoc-Dien Trinh, MD, MBA, describe what participants can expect from this unique experience and highlight important topics in the curriculum.


AAOS 2023: Resident Involvement in Open Reduction, Internal Fixation Did Not Increase Adverse Events

George S. M. Dyer, MD, a surgeon at the Brigham, presented research at the American Academy of Orthopaedic Surgeons Annual Meeting in Las Vegas showing that resident involvement in open reduction and internal fixation (ORIF) for distal radius fracture showed no difference in rates of episode-of-care adverse events.