Choroid Plexus Enlargement May Indicate Psychosis Onset

Because of the size, shape, and location of the choroid plexus (ChP), it’s difficult to use automated MRI to determine its volume. Brigham and Women’s Hospital researchers developed the first MRI manual segmentation method for investigating ChP, and they observed significant ChP enlargement in early-course psychosis.


Using Video Interpretation to Enhance Care for Patients With Limited English Proficiency

Doctor and patient look at tablet, smiling; video interpretation in medical setting

Regan W. Bergmark, MD, a sinus and endoscopic skull base surgeon, is co-leading a project to advance language-concordant care in otolaryngology-head and neck surgery across the Mass General Brigham system. The team is trialing a mobile app that provides patients and physicians with live video interpretation on demand.


Clinic Screens High-Risk Patients to Reduce Incidence of Anal Cancer

HSIL pathology slide

A Brigham clinic offers high-resolution anoscopy to screen for anal dysplasia in people at increased risk of anal cancer due to HPV infection, HIV status, and other factors. Co-founders James Yoo, MD, and Jennifer A. Johnson, MD, explain their mission to reduce the incidence of anal cancer in high-risk populations.


Economic Burden of Neuromyelitis Optica Spectrum Disorders Quantified From Patient Point of View

Brigham and Women’s Hospital researchers recently conducted the first study of patient-reported data on the economic burden of neuromyelitis optica spectrum disorders (NMOSD). Specifically, they characterized the direct and indirect costs of relapse events (ED visits and hospitalizations).


Brigham Team Discovers Mechanism of Th17 Cell Production in the Gut

Rendering of Interleukin 17, a cytokine produced by T-helper cells, on black background

Brigham and Women’s Hospital recently determined how epithelial cells promote Th17 cell generation in response to bacterial colonization as a step toward better understanding the treatment—and even prevention—of chronic inflammatory diseases.


Embedding Diabetes Care in the Latino Community

Headshot of A. Enrique Caballero, MD on gray background

The Brigham’s new approach to providing diabetes care for Latino/Hispanic patients involves embedding diabetes specialists in community clinics and offering culturally and linguistically appropriate services to help patients control their disease and its complications, as A. Enrique Caballero, MD, explains.


AAOS 2023: Andrew J. Schoenfeld, MD, Discusses the Cost-Utility Benefits of Robotic Assistance for Adult Spinal Deformity Procedures

In this video from the 2023 American Academy of Orthopaedic Surgeons Annual Meeting, Professor Andrew J. Schoenfeld, MD, describes his recent research on the cost-utility benefits of robotic assistance for adult spinal deformity procedures.


Variants of AAV9 Efficiently Cross the Blood–Brain Barrier in Non-Human Primates

Researchers at Brigham and Women’s Hospital have designed two promising AAV9 variants that are much more effective than the parent vector for delivering therapeutic transgenes into the central nervous system of mice and macaques.


People Have “Massive” Memory for Where and When They Saw Something

Researchers at Brigham and Women’s Hospital have shown more specifically that humans have a spatial massive memory—they can remember where they saw objects presented briefly—and a temporal massive memory—they can remember when they saw the objects.


New Online Tool Calculates Patient-specific “Safe Zones” for Acetabular Component Positioning During THA

3D illustration of pelvic bone and femur, with total hip arthroplasty installed

Researchers at Brigham and Women’s Hospital have created a quantitative tool that can be used for patient-specific preoperative planning and intraoperative adjustment of acetabular component position during total hip arthroplasty, with or without assistive intraoperative technology.