Ketamine Is Noninferior to ECT for Nonpsychotic Treatment-resistant Major Depression

Amit Anand, MD, director of Psychiatry Translational Clinical Trials at Brigham and Women’s Hospital, conducted ELEKT-D, a pragmatic comparative-effectiveness trial of ketamine and ECT for nonpsychotic treatment-resistant major depression.

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The Brigham Keeps Women’s Cardiovascular Health in the Spotlight

The fact that cardiovascular disease is the leading cause of death in women is wildly underappreciated, says the Brigham’s JoAnn E. Manson, MD, MPH, DrPH. Dr. Manson has led many seminal research projects focused on women’s health and set the foundation for related advances at the Brigham today.

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First-in-Human Trial: Ingestible Pill Accurately Monitors Respiration and Cardiac Activity

Ingestible devices have been researched since the 1950s, and proof-of-concept trials support their ability to measure pH, temperature, and gastrointestinal motility. Giovanni Traverso, MB, BChir, PhD, and colleagues have developed a vitamin-sized pill that measures respiratory rate and heart rate.

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A Practical Guide to Implementing ACGME Geriatric Medicine Milestones 2.0

The Accreditation Council for Graduate Medical Education has updated its Milestones tool for assessing geriatrics fellows. Shoshana Streiter, MD, and colleagues outlined a four-step process for geriatric fellowship programs to transition from the original Milestones to Milestones 2.0.

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Risk Factors Identified for Repeat COVID-19 in Patients With Systemic Autoimmune Rheumatic Diseases

Jeffrey Sparks, MD, MMSc, and colleagues recently completed the first study of risk factors for repeat COVID-19 in an immunocompromised population. They report that use of rituximab, use of methotrexate, and younger age increased the risk of repeat COVID-19 among patients with systemic autoimmune rheumatic diseases.

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AAOS 2024: Brigham Orthopaedic Experts Present

From February 12 – 16, experts from the Department of Orthopaedic Surgery at Brigham and Women’s Hospital will present their latest research at the 2024 American Academy of Orthopaedic Surgeons Annual Meeting in San Francisco.

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Take-Home Surgical Simulation Model Allows Senior Trainees to Practice Airway Anastomosis

Researchers at Brigham and Women’s Hospital and the University of Toronto have developed and validated a portable model that helps trainees perfect complex vascular surgery and airway anastomosis techniques. The model is inexpensive and is the first to simulate tracheal anastomosis.

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Factors Identified That Predict Long-term Survival After Cervical Deformity Surgery

Andrew Schoenfeld, MD, MSc, of the Department of Orthopaedic Surgery at Brigham and Women’s Hospital, and colleagues have completed the first long-term (10-year) survival analysis after adult cervical deformity surgery. They say preoperative BMI, preoperative frailty status, and fusion length affected mortality rates.

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Review: Dural and Extradural Cavernous Venous Malformations

Neurologist and Neurosurgeon Talk, Use Computer, Analyse Patient MRI Scan, Diagnose Brain. Brain Surgery Health Clinic Lab: Two Professional Physicians Look at CT Scan. Close-up

In a two-part article in the Journal of Neurosurgery, surgeons at Brigham and Women’s Hospital discuss the epidemiology, clinical and radiologic features and surgical management of this group of pathologies. This summary covers part 1, dural and extradural CavVMs.

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SocialBit: A Wearable Sensor to Quantify Social Isolation

Researchers at Brigham and Women’s Hospital have developed SocialBit, a smartwatch-based sensor designed to track the number and duration of daily interactions of the person wearing it.

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