Latest Clinical & Research News
Specialty: Endocrinology
The “glycemic gap” has previously been validated as a predictor of severe acute illness. Now, Brigham and Women’s Hospital researchers have extended the glycemic index’s utility to COVID-19.
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To address conflicting evidence, Meryl S. LeBoff, MD, JoAnn E. Manson, MD, PhD, MPH, and colleagues conducted an ancillary analysis of the Vitamin D and Omega-3 Trial (VITAL). They found vitamin D did not affect fracture risk in the general population.
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Caroline M. Apovian, MD, and team determined that the variability of weight loss and hemoglobin A1C across racial/ethnic groups was small after Roux-en-Y gastric bypass (RYGB) compared with sleeve gastrectomy (SG). However, safety concerns were greater for Black and Latino patients after RYGB than SG.
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Brigham researchers are looking at novel ways to boost natural mechanisms that the body uses to counteract the pathogenesis of obesity and its complications. An upcoming clinical trial led by Mehmet Furkan Burak, MD, explores the impact of dietary supplementation with palmitoleic acid in obese, prediabetic individuals.
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SGLT2 inhibitors like dapagliflozin reduce hospitalization for heart failure and progression of diabetic nephropathy in patients with type 2 diabetes, but decrease systolic and diastolic blood pressure only minimally. Brigham researchers investigated whether their efficacy might depend on pre-treatment blood pressure.
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An analysis of prospectively collected data has demonstrated that adults who sustain traumatic brain injury (TBI), regardless of age and injury severity, are at higher risk of certain cardiovascular, endocrine, neurologic, and psychiatric disorders.
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A study showed patients with a history of bariatric surgery had lower overall complication rates after spinal surgery than morbidly obese patients who did not have bariatric surgery. Now researchers report significant reductions in symptomatic spinal disorders and the need for spinal surgery after bariatric surgery.
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David J. Cote, MD, PhD, and Meir J. Stampfer, MD, DrPH, of the Channing Division of Network Medicine at Brigham and Women’s Hospital, and colleagues have conducted the first prospective study of associations between pituitary adenoma and the use of oral contraceptives or menopausal hormone therapy.
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In 2018, Pichamol Jirapinyo, MD, MPH, and Christopher C. Thompson, MD, developed a modified technique they call distal POSE—which involves placing plications primarily in the gastric body, sparing the fundus. They have published a one-year study, concluding distal POSE appears safe and effective for treating obesity.
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Vanita Aroda, MD, associate physician in the Division of Endocrinology, Diabetes and Hypertension, has served as a clinical researcher and clinical trialist for countless studies focused on preventing and treating type 2 diabetes. She discusses her involvement in the SELECT, PIONEER 1, REVITALIZE 1, and other trials.
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